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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Treating non-classic congenital adrenal hyperplasia is complex because the benefits of hormone treatment must be weighed against potential health risks.

Blocking the prolactin receptor might help treat various diseases, but more research is needed.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Sansevieria trifasciata Prain shows promise for treating hair loss by inhibiting androgen receptors.

Finasteride may affect PNMT, causing side effects.

DHT affects testicular development and regulates spermatogenesis in some fish.

11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Birth control pills with low-dose estrogen and antiandrogenic progestins can effectively treat acne.

Neurosteroids show promise for treating epilepsy and more research is needed.

Indian jujube has many medicinal properties and can help treat ailments like diabetes, inflammation, and cancer.

A new plant-based treatment was effective for hair regrowth in women with a specific type of hair loss that didn't respond to usual treatments.

We need better ways to test and understand SARMs to make safer and more effective treatments.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.

Testosterone therapy can help women with androgen deficiency by improving energy, sex drive, and bone health with few side effects.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Hormonal therapies are safe and effective for treating acne in female adolescents, with specific treatments for those with endocrine disorders.

Perilla frutescens, an East Asian plant, contains 400 bioactive compounds that have various health benefits, including anti-inflammatory, antidepressant, and anticancer effects, and can treat conditions like diabetes, skin allergies, and neurological disorders.

Girls with PCOS have higher levels of certain androgens, which are linked to excess hair growth, but these androgens don't help diagnose PCOS.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.