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This review discusses the role of keratins in maintaining epidermal structure and function and reports no new results; the authors emphasize the lack of rational therapies for skin disorders linked to keratin mutations.

In this study, carboxymethylalanyl disulfide keratin was shown to effectively prevent hair damage during repeated bleaching and permanent waving treatments.

This study found that CMAD wool keratin may protect human hair from damage during repeated bleaching and permanent waving treatments.

This Ph.D. project aims to evaluate the self-assembling potential of hair keratin extracts and study the cellular response to both crude and purified keratins, highlighting their potential applications from biomedical to water remediation.

This review summarizes the cell type distribution and functional significance of human keratins, emphasizing their roles in tumor diagnosis and potential clinical applications, and reports no new clinical findings.

This study revealed that human keratin-associated protein genes are expressed in specific patterns in hair fiber regions and vary in size, with some variations distinct across different populations.

This study suggests that the keratins found in reptile and bird skin appendages evolved independently from mammalian hair keratins, highlighting convergent evolution in these species.

In this study, topical application of keratin extract from wool promoted hair growth in mice by reducing the time for initiation and completion of growth phases and improving hair quality.

This study suggests that Keratin 6hf may be a potential marker of oral squamous cell carcinoma and could play a role in its progression, though further research is needed to understand its function.

This study demonstrated that cryogelation of human hair keratin allows the development of 3D scaffolds with tunable properties, supporting cell adhesion and proliferation for potential biomedical applications.

This study suggests that specific combinations of human type I and II hair keratins, particularly K35-K85 and K36-K81, have distinct in vitro assembly properties that are significant for macrofibril formation.

This review discusses the role of keratins in epithelial cell stress protection and cancer, highlighting their potential as multifunctional regulators and diagnostic markers, without presenting new research findings.

This study identified a 69 bp deletion in the KRT75 gene as the cause of the frizzle feather trait in chickens, affecting feather curling.

This study used proteomics to identify various proteins in human hair, which may help develop novel biomarkers for hair health, disease, and aging.

Keratin peptides can change hair shape gently without harsh chemicals.

This study found that cysteine supplementation significantly increases keratin expression in human keratinocytes, and counteracts the negative impact of iron deficiency on keratin production by enhancing iron availability for cellular processes.

This study used proteomic techniques to analyze human hair proteins, revealing keratin heterogeneity and identifying posttranslational modifications, such as cysteine trioxidation and methylation.

This article reviews the role of keratins in epithelial function and structure, discussing their involvement in growth control, organelle functions, and pathomechanisms of disorders, but reports no new clinical results.

This review discusses recent advancements in understanding neuroendocrine regulation of keratin biology and highlights the potential of neurohormones to treat skin disorders, but it reports no new clinical results.

This study proposes a new method to selectively isolate keratin-associated proteins and keratin from human hair, suggesting that KAPs may support keratin fibers in hair structure.

This study observed that genetic variation in the ovine KRTAP22-1 gene is linked to increased wool yield and decreased fiber curvature in sheep, indicating its potential use in breeding programs.

In this study, researchers found that L-cysteine interacted electrostatically with anionic ions on the surface of keratin fibers in human hair, reducing the rate of disulfide bond disconnection at pH 9.0.

This study developed O/W hair mask emulsions with collagen hydrolysate, keratin, and natural oils, reporting that they are stable, physiologically acceptable for skin, creamy, non-greasy, and hydrophilic, with properties suitable for cosmetic applications in hair care.

This study suggests that adjusting the ratios of keratin-associated proteins to keratin intermediate filaments can create keratin/chitosan hydrogels with more consistent gel properties for tissue engineering.

This study identified a missense mutation in the keratin 71 gene as the cause of autosomal dominant woolly hair/hypotrichosis in a Japanese family, marking the first human mutation in KRT71 linked to a hair disorder.

This study found that injecting keratin into the skin of mice promoted hair growth, potentially through keratin's interaction with hair-forming cells and changes in the microenvironment.

This study utilized advanced imaging techniques to quantify hair damage and dye uptake dynamics, revealing that compound penetration in hair is influenced by molecule size and lipophilicity.

This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.

This review discusses immunohistological and immunofluorescent methods for studying the human hair follicle cell cycle, reporting no new results, and suggests its potential for advancing cell cycle research.

In this study, photodynamic therapy was found to achieve permanent reduction of nonpigmented hair in mice, unlike an 800-nm diode laser, by targeting the hair matrix through repeated sessions.