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    Glossary High-Grade Prostate Cancer

    more aggressive, rapidly growing prostate cancer with higher Gleason scores

    High-Grade Prostate Cancer refers to a more aggressive and rapidly growing form of prostate cancer, often characterized by a higher Gleason score (typically 8-10). This type of cancer is more likely to spread to other parts of the body and requires more intensive treatment compared to lower-grade prostate cancers.

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    1. THERAPEUTIC HOTLINE: Treatment of androgenic alopecia with finasteride may result in a high grade prostate cancer in patients: fact or fiction? Dermatologic Therapy · 2010 · 9 citations
    2. The Dark Side of 5α-Reductase Inhibitors' Therapy: Sexual Dysfunction, High Gleason Grade Prostate Cancer and Depression Korean Journal of Urology · 2014 · 75 citations
    3. The association of male pattern baldness and risk of cancer and high-grade disease among men presenting for prostate biopsy Canadian Urological Association journal · 2016 · 3 citations
    4. A Chance Finding of High Grade Prostate Cancer in a 35-Year-Old Male – A Case Report and Outcomes of Robotic Radical Prostatectomy in Young Men with Prostate Cancer Research and reports in urology · 2023
    5. Finasteride-its impact on sexual function and prostate cancer Journal of Cutaneous and Aesthetic Surgery · 2009 · 33 citations
    6. The Risks and Benefits of 5α-Reductase Inhibitors for Prostate-Cancer Prevention 2011 · 147 citations
    7. Relationship of Early-Onset Baldness to Prostate Cancer in African-American Men Cancer Epidemiology, Biomarkers & Prevention · 2013 · 21 citations
    8. Androgenetic alopecia at various ages and prostate cancer risk in an equal-access multiethnic case–control series of veterans Cancer Causes & Control · 2013 · 12 citations
    9. Male alopecia, finasteride, and cancer risk Community oncology · 2012
    10. Guidelines on the use of finasteride in androgenetic alopecia Indian Journal of Dermatology, Venereology and Leprology · 2016 · 33 citations
    11. EP1446 - ECE_2942 - Finasteride for treatment of androgenic male alopecia since puberty: case report European Journal of Endocrinology · 2026
    12. A cornerstone of hematological science Community oncology · 2012
    13. Propecia: The Goose That Lays the Golden Eggs Skinmed · 2005
    14. Steroidal 5α-reductase and 17α-hydroxylase/17,20-lyase (CYP17) inhibitors useful in the treatment of prostatic diseases The Journal of Steroid Biochemistry and Molecular Biology · 2013 · 51 citations
    15. Off-label prescriptions: patient safety first The Lancet Oncology · 2011 · 4 citations
    16. 1262 ONE YEAR FINASTERIDE THERAPY IN MEN WITH A SERUM PSA GREATER THAN 4 NG/ML WHO HAD UNDERGONE REPEAT BIOPSY The Journal of Urology · 2012
    17. Finasteride Counseling for Male Androgenetic Alopecia Should Reflect Updated Findings on Prostate Cancer Risk Skin appendage disorders · 2020 · 1 citations
    18. Androgenetic alopecia and prostate cancer: findings from an Australian case-control study. PubMed · 2002 · 21 citations
    19. Prostate cancer incidence among finasteride and alpha-blocker users in the Finnish Prostate Cancer Screening Trial British Journal of Cancer · 2009 · 49 citations
    20. Five-alpha-reductase Inhibitors for prostate cancer prevention. The Cochrane library · 2008 · 37 citations
    21. Possible association between androgenic alopecia and risk of prostate cancer and testicular germ cell tumor: a systematic review and meta-analysis BMC Cancer · 2018 · 3 citations
    22. Association Between 5α-Reductase Inhibitors and Prostate Cancer Mortality The International Journal of Medical Science and Health Research · 2024 · 1 citations
    23. Alcohol and Prostate Cancer: Time to Draw Conclusions Biomolecules · 2022 · 9 citations
    24. Role of 5 alpha-reductase inhibitors in the management of prostate cancer Clinical interventions in aging · 2006 · 15 citations
    25. A new look at an old option in the treatment of early-stage prostate cancer: hormone therapy as an alternative to watchful waiting Medical hypotheses · 1998 · 5 citations
    26. Finasteride: Middle-Age Cure-All for Alopecia and Benign Prostatic Hyperplasia? Mayo Clinic Proceedings · 2006
    27. The Role of 5αR Inhibitors in the Early Growth of Pca Cells Urologia Journal · 2005
    28. Finasteride: Middle-Age Cure-All for Alopecia and Benign Prostatic Hyperplasia?–Reply–I Mayo Clinic Proceedings · 2006 · 2 citations
    29. Regarding prostate-specific antigen: let's not shoot the messenger QJM · 2011 · 3 citations
    30. Urological Oncology: Prostate Cancer The Journal of Urology · 2008