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Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Early detection and comprehensive treatment of PCOS are crucial due to its long-term health impacts and associated risks.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Black ethnicity, prior PSA tests, enlarged prostate, and family history increase prostate cancer risk; Asian ethnicity, obesity, smoking, diabetes, and less sexual activity or no children decrease risk.

Edible seeds from the Cucurbitaceae family like pumpkin and watermelon seeds are nutritious and may have health benefits, but eating too much can cause side effects.

SLE patients need careful diagnosis to distinguish infections from disease flares for proper treatment.

Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.

Severe insulin resistance can be managed with medication, lifestyle changes, and treatment for related conditions.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

MC4R gene variants not linked to female hair loss.

Common cosmetic dermatology techniques improve skin damaged by the sun and aging.

Vitamin D is crucial for health, and deficiency can cause hair loss and other health issues.

Chemicals and body size might change when puberty starts and progresses, but more research is needed to confirm this.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Tinea capitis is a common scalp infection causing hair loss, mostly in young children.

The document concludes that Functional Hypothalamic Amenorrhea should be carefully diagnosed and managed to prevent health complications, using lifestyle changes and specific medications.

Dutasteride may help shrink prostate cancer tumors.

The visfatin GT genotype may increase the risk of Alopecia Areata.

Alk1 in specific cells is crucial for proper nerve branching and hair function.

The document concludes that personalized treatment, including lifestyle changes and medication, is essential for managing PCOS in teenagers, while also addressing their psychological well-being.

Men with severe hair loss may have poorer sperm quality.

Mutations in NIPAL4 cause skin issues by disrupting lipid layers, but some improvement is seen with topical treatment.

There are various effective hormone treatments for puberty induction in boys and girls with hypogonadism, and starting treatment early is important.

Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.

Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.

Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.