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Mouflon rams mature gradually with changes in body, horns, and hormones linked to age and seasons, reaching full sexual maturity well after puberty.

The document explains how male reproductive hormones work and affect the body.

Finasteride affects young male rats' brain function and behavior negatively.

South Asian women with PCOS are more likely to have metabolic issues and central obesity, and simple measures like waist size and blood pressure can help identify these risks early.

PCOS increases sexual pain distress in infertile women.

Diagnosing PCOS in teenagers is challenging and should use strict criteria to avoid misdiagnosis and unnecessary worry.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

Metformin is safe in early pregnancy for women with PCOS and may reduce certain risks.

The first in-prison dermatology clinic in the U.S. faced challenges and found certain skin conditions common among inmates, with rare cases of serious skin cancer.

Women with PCOS have more severe liver disease.

Ovarian drilling surgery is not clearly better than medical treatments for PCOS symptoms.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

The guidelines help doctors diagnose and treat hormone-related disorders in women.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Evaluating various physical and health factors helps diagnose polycystic ovarian syndrome (PCOS).

The document concludes that hirsutism can be managed with various treatments tailored to the individual, potentially improving quality of life.

Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.

Most women with hirsutism have it because of PCOS, and they need long-term treatment including medication and hair removal to improve their condition.

Hair loss might be due to nerve issues, treatable with electric stimulation or acupuncture.

Hyperandrogenism increases heart disease risk in premenopausal women, but this risk is linked to obesity in postmenopausal women.

PCOS is linked to a higher risk of endometrial cancer but not ovarian or breast cancer, and more research is needed on its role in cancer development and treatment effects.

Masculine facial features may not reliably indicate heritable health, and more research is needed.

Women with epilepsy should be monitored for reproductive issues, which can be caused by epilepsy or its treatments, especially when using valproate.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

Manage PCOS in primary care with weight loss, psychological support, medication, and monitoring for health risks.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.