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Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Hirsutism is mainly caused by high androgen levels or sensitivity, with PCOS being the most common cause.

A 71-year-old woman developed male-like features due to high testosterone levels caused by a benign ovarian tumor, which was successfully removed by surgery.

Ovarian stromal hyperplasia can cause high testosterone in postmenopausal women and is treated by removing the ovaries.

The case highlights the complexity of diagnosing high testosterone in older women and the need for thorough testing.

The conclusion is that there's a link between high testosterone levels, insulin resistance, and certain skin conditions, regardless of obesity.

PDRN helps repair tissue and improve wound healing with a high safety profile.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Nelumbinis Semen extract helps hair grow and could prevent hair loss.

A woman's excessive hair growth was linked to a rare case of high testosterone caused by a prolactin-producing pituitary tumor.

A 77-year-old woman with hair loss had high testosterone and 17OH-progesterone levels, but no significant findings on imaging.

Ethosomes can safely and effectively deliver various drugs deep into the skin.

Azathioprine caused side effects in over half of the Korean pediatric inflammatory bowel disease patients, requiring close monitoring.

A woman with lupus experienced skin death due to a blood clotting disorder after stopping a blood thinner, which healed with treatment.

MCTD should be considered in children with recurring muscle issues, lupus-like symptoms, and edema.

Removing a hormone-producing adrenal tumor can stop hair loss in women with high testosterone levels.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

The research found that anovulatory young women have higher androgen and hormone levels than those who ovulate, suggesting immature hormonal regulation rather than a specific condition.

Cardiovascular disease deaths decreased but still caused one-third of U.S. deaths in 2007, with high rates of hypertension, smoking, obesity, and diabetes.

Terbinafine and itraconazole are more effective against Microsporum canis than fluconazole and griseofulvin.

Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.

Signaling pathways are crucial for hair growth in goats.

Disrupting the Flcn gene in mice causes early kidney cysts and tumors, which can be treated with rapamycin.

Finasteride cream helps hair growth with less side effects.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Metabolic syndrome linked to female hair loss; waist size and high blood pressure important factors.

Finasteride effectively prevents biofilm formation and treats preformed biofilms, but requires high doses.

Young female Australian fur seals are losing hair due to low tyrosine and zinc levels and high pollution exposure.

The cat's hypothyroidism was successfully managed with levothyroxine, leading to a stable condition.

Hair restoration surgeons have improved follicular unit excision (hair transplant method) by using innovative tools and techniques, reducing hair damage and increasing success rates.