11 citations
,
January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)” This case report observed that while a 4-year-old boy with vitamin D-dependent rickets type II showed biochemical and bone improvement after vitamin D and calcium treatment, his alopecia did not improve.
7 citations
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April 1996 in “Archives of dermatological research” This study found that after topical application in rats, 1,24-dihydroxyvitamin D3 absorbed through both the stratum corneum and hair follicles, with about 30% excreted via the faeces.
6 citations
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March 2018 in “Proceedings - Baylor University. Medical Center” This case report describes a patient with sarcoidosis who experienced severe symptomatic hypercalcemia, scarring alopecia, and acute-on-chronic kidney failure.
3 citations
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August 2018 in “Therapeutics and Clinical Risk Management” This case report discusses a young woman who developed bilateral osteonecrosis of the femoral head after corticosteroid treatment for alopecia areata, underscoring the risk of this complication in patients undergoing such therapy.
May 2023 in “Frontiers in Endocrinology” This review article discusses recent updates on the skin manifestations associated with thyroid disease, emphasizing their role as early indicators of thyroid hormone dysregulation.
This study in a nine-year-old boy from Lebanon identified a gene mutation (c.1066dup p.(Arg356Profs*16)) associated with a rare inborn error of immunity, characterized by craniosynostosis, jaundice, and several other symptoms, expanding the known genotypic and phenotypic spectrum of this condition.
160 citations
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June 2008 in “American Journal Of Pathology” This review discusses the effects of the epidermal growth factor receptor system on skin biology and pathology, relying on animal models to analyze roles in cellular processes, wound healing, and tumorigenesis, but reports no new results.
99 citations
,
September 2007 in “The American journal of pathology” This study found that organ-cultured human scalp hair follicles can mimic chemotherapy-induced damage in vivo and serve as a model to explore molecular targets and protective agents for hair follicle preservation.
97 citations
,
March 2009 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study suggests that there is a U-shaped relationship between vitamin D hormonal forms and aging, with an optimal serum calcidiol concentration needed to minimize aging-related chronic disease risk.
15 citations
,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.
5 citations
,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” This study described the clinical and genetic features of two Iranian siblings with hereditary vitamin D resistant rickets, identifying a specific VDR gene mutation contributing to their symptoms.
4 citations
,
December 2019 in “Trials” This study aims to evaluate the effectiveness of YH0618 granules in preventing chemotherapy-induced hair loss in breast cancer patients through a randomized, double-blind, multi-center clinical trial, focusing on potential mechanisms related to kidney deficiency as understood in Chinese Medicine. Results are not yet reported.
2 citations
,
September 2021 In this study, serum 25-hydroxyvitamin D levels were similar between alopecia areata patients and healthy controls, though a non-significant trend toward higher vitamin D deficiency was observed among the patients.
November 2020 in “IntechOpen eBooks” This review discusses the role of mineral nutrients in human health, emphasizing the importance of dietary sources and education to prevent mineral deficiencies, and reports no new clinical results.
173 citations
,
August 2015 in “Developmental cell” This study characterizes gene expression patterns in embryonic hair follicle progenitors and their niche, identifying signaling pathways like axon guidance that may drive cellular rearrangements for hair follicle formation.
154 citations
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October 1996 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that 17-beta-estradiol inhibits hair growth in mice by blocking hair follicles in the telogen phase, whereas an estrogen receptor antagonist promotes hair growth by initiating anagen.
83 citations
,
January 2023 in “Development” This review provides an overview of Hox genes, focusing on their evolutionary history, genomic organization, and roles in development, but reports no new study results.
56 citations
,
February 2012 in “Developmental biology” This study found that the absence of Sostdc1 in mice alters mammary gland and hair follicle development, particularly by increasing vibrissae numbers and causing unusual nipple-like structures.
37 citations
,
March 2020 in “Molecules” This review outlines the adverse effects of glucocorticoid excess on bones, adipose tissue, brain, and skin, with a focus on the Wnt/β-catenin pathway, and reports no new research findings.
17 citations
,
October 2005 in “Journal of Biological Chemistry” This study found that Hirosaki hairless rats experience transient activation of STAT5A in the mammary glands during early lactation, involving O-GlcNAc modification rather than Tyr-phosphorylation.
14 citations
,
November 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that platelet-rich plasma injections were more effective than hyaluronic acid in improving survival rates, reducing re-intervention, and enhancing patient satisfaction for mid-term knee osteoarthritis treatment.
10 citations
,
June 2019 in “Journal of the European Academy of Dermatology and Venereology” This article discusses the updated European Training Requirements for the specialty of Dermatology and Venereology, emphasizing the harmonization of curriculum to improve specialist training across Europe, and reports no new clinical results.
3 citations
,
November 2021 in “World Journal of Clinical Pediatrics” This study observed that vitamin D therapy may help manage alopecia areata, totalis, and universalis, with promising hair regrowth in some pediatric cases, though further trials are needed.
1 citations
,
August 2024 in “Journal of Morphology” This study observed that developing mammary organs in Monodelphis domestica show mammary hairs in 12-week-old females, which disappear by 18 weeks, with findings suggesting shared characteristics between their nipples and eutherian nipples, supporting the evolutionary link between mammary glands and hair organs.
1 citations
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August 2023 in “Diagnostics” This study observed that women with Polycystic Ovary Syndrome, particularly those with specific phenotypes, had a significantly higher risk of developing kidney stones compared to healthy controls.
May 2026 in “Discover Oncology” This review discusses the role of LGR4 in tumors, highlighting its involvement in cancer progression, metastasis, and chemotherapy resistance, as well as its regulatory effects on tumor stem cell self-renewal and stem cell characteristics, based on multiple recent studies.
December 2025 in “Journal of Cell Communication and Signaling” This review discusses the role of vitamin D receptor signaling in hair follicle biology for alopecia treatment and underscores the need for continued research, without presenting new clinical results.
September 2024 in “Clinical Case Reports” This case report highlights a rare presentation of APS-1 in a 28-year-old Pakistani male with cardiovascular and pulmonary symptoms, illustrating the importance of early recognition and multidisciplinary management for improved patient outcomes.
61 citations
,
April 2023 in “Bioactive Materials” This review article highlights recent advances in microneedle technology for wound healing and tissue regeneration, discussing various cargo types, structural designs, and fabrication methods, and suggesting guidelines for designing microneedle systems tailored to specific applications.
5 citations
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November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.