March 2026 in “Journal of Pakistan Association of Dermatologists” This study found that androgenic alopecia is highly prevalent in women with PCOS, suggesting early dermatological screening could help identify related metabolic and psychosocial risks.
December 2025 in “Journal of Skin and Stem Cell” This study found a higher prevalence of lipid abnormalities in individuals with androgenetic alopecia, especially in severe cases, highlighting the need for early screening and treatment to prevent cardiovascular complications.
November 2025 in “Basic and Clinical Andrology” This systematic review and meta-analysis found that male first-degree relatives of women with PCOS have increased rates of metabolic issues, hormonal imbalances, and androgenic features compared to controls, suggesting a male equivalent of PCOS.
March 2025 in “Journal of Pakistan Association of Dermatologists” This study observed that 62.7% of men with androgenetic alopecia had abnormal blood lipid levels, suggesting the importance of assessing lipid profiles in these individuals for early detection of cardiovascular and metabolic risks.
This study found that androgenetic alopecia in men was significantly associated with dyslipidemia, particularly in more severe cases, suggesting it could be a marker for systemic illness.
December 2023 in “Advances in basic medical sciences.” In this cohort study, short-term treatment with metformin in overweight/obese women with PCOS significantly improved menstrual irregularities and lipid profiles (HDL and LDL levels), but did not significantly affect BMI, insulin, testosterone, or adipokine levels compared to the unexposed group.
October 2023 in “Benha Journal of Applied Sciences” This study found that male patients with androgenetic alopecia had lower serum levels of the antioxidant enzyme paraoxonase 1 compared to healthy controls.
September 2023 in “JEADV Clinical Practice” This study reviewed existing literature and found that androgenic alopecia may be associated with cardiovascular risk factors, while evidence for alopecia areata and cicatricial alopecias is limited and sometimes contradictory.
September 2023 in “PubMed” This study reviewed baricitinib's efficacy and safety for treating alopecia areata and found that more patients achieved significant hair regrowth with baricitinib compared to placebo in two phase III trials. Mild to moderate side effects were reported, with additional study suggested for long-term effects.
March 2017 in “Iraqi Journal of Pharmaceutical Sciences” This study found that Iraqi male bodybuilders abusing anabolic androgenic steroids experienced significant changes in sex hormones, liver and kidney function, and lipid profiles compared to non-AAS-using controls.
May 2012 in “15th International & 14th European Congress of Endocrinology” Taking 1mg finasteride tablets for 6 months can lower good cholesterol (HDL) and raise triglycerides in men with hair loss.
June 2021 in “Egyptian Journal of Dermatology and Venereology” This study found that psoriasis, acne, and androgenetic alopecia are associated with an atherogenic lipid profile, suggesting an increased risk of atherosclerosis and cardiovascular disease, especially among psoriasis patients.
January 2021 in “Menoufia Medical Journal” This study found that patients with early-onset androgenetic alopecia had significantly higher levels of fasting blood sugar, triglycerides, and cholesterol, suggesting an increased risk of developing coronary artery disease.
October 2018 in “International Journal of Research in Dermatology” In this study, androgenetic alopecia patients had a significantly higher prevalence of metabolic syndrome and related metabolic disorders compared to those without the condition.
December 2013 in “Tehran University Medical Journal TUMS Publications” In this study, no significant relationship was found between androgenetic alopecia and hyperlipidemia, but higher levels of cholesterol, LDL, and triglycerides in AGA patients may suggest an increased risk of coronary heart disease.
June 2021 in “Current developments in nutrition” This study found that high doses of finasteride were associated with reduced total cholesterol and body weight gain in LDLR-deficient mice.
December 2021 in “Benha Journal of Applied Sciences” This study found that high serum alarin levels were linked to both androgenetic alopecia and metabolic syndrome, increasing with the severity of AGA.
177 citations
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December 2002 in “The Lancet” In this study, single fibrinogen/LDL apheresis showed a significant improvement in speech perception for patients with plasma fibrinogen concentrations over 295 mg/dL compared to standard treatment for sudden sensorineural hearing loss.
October 2002 in “Atherosclerosis Supplements” LDL apheresis lowers inflammation and cardiovascular risk by reducing CRP levels long-term.
December 2015 in “Vascular Pharmacology” Different cells affect hair follicle blood vessels, endothelial cells react differently to inflammation and oxidized fats, and prasugrel better protects heart vessels during a procedure than clopidogrel.
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June 2018 in “Journal of Diabetes, Metabolic Disorders & Control” This study found that women with polycystic ovary syndrome have higher triglyceride and fasting glucose levels in obese individuals and higher total cholesterol levels in non-obese individuals compared to healthy women.
18 citations
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August 2019 in “Nutrients” In this study, lifelong barley intake in SAMP8 mice was associated with extended lifespan, improved aging-related phenotypes, and beneficial shifts in the intestinal microbiome.
31 citations
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February 2021 in “Nutrients” This study found that curcumin may improve glycemic control and certain aspects of lipid metabolism in patients with polycystic ovary syndrome.
October 2018 in “International journal of reproduction, contraception, obstetrics and gynecology” In this study, dyslipidemia was found to be prevalent among young adult women with polycystic ovary syndrome in Port Harcourt, Nigeria, particularly characterized by increased triglycerides and decreased HDL-c levels.
This study observed that women with polycystic ovary syndrome showed hormonal changes and higher post-meal lipemia compared to healthy controls, alongside endothelial dysfunction potentially detectable before insulin resistance.
3 citations
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August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found that women with PCOS had significantly elevated plasma levels of PAI-1, which correlated with insulin resistance and obesity.
1 citations
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April 2021 in “Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine” This study found that women with polycystic ovary syndrome in the Black Sea Region had higher levels of androgens, obesity, and insulin resistance, increasing their risk of metabolic syndrome compared to healthy women.
1 citations
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February 2013 in “African Journal of Pharmacy and Pharmacology” This study found that in patients with androgenetic hair loss, taking 1 mg of finasteride daily significantly raised triglyceride levels and decreased HDL levels after 3 and 6 months.
This study reported that high cholesterol levels were linked to increased prostate cancer risk, while selenium supplementation affected gene expression, suggesting nutritional and clinical factors might influence prostate cancer risk and biology.
January 2014 in “S. Karger AG eBooks” Type 2 diabetes in youth is increasing, with high treatment failure rates and more severe than Type 1; certain drugs can lower lipid levels effectively with varying side effects, and apples may benefit heart health like statins but with fewer side effects.