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The flexible fixed-sequence testing method allows for more effective evaluation of multiple goals in a clinical trial while controlling the risk of false positives.

The document suggests a possible link between Crohn's disease and Johne's disease and calls for more research.

Working night shifts for four days can lower the body's ability to use insulin, which may increase the risk of type 2 diabetes.

Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.

Male hormones, or androgens, affect women's health in areas like mood and bone density, and hormone replacement therapy using antiandrogenic progestogens can improve mood disorders and alertness in menopausal women.

Pumpkin seed oil helps hair growth in men with hair loss.

Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.

People with psoriasis are more likely to have Metabolic Syndrome than those without psoriasis.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Tretinoin cream boosts minoxidil absorption, possibly improving hair loss treatment.

Vegetarian Indian women with PCOS have higher inflammation levels than non-vegetarians.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Diagnosing PCOS in teenagers should focus on signs of excess male hormones and not rely solely on ovarian ultrasound or irregular periods, and should be reassessed in adulthood.

PCOS may start before birth, involves metabolic issues, and can be treated with drugs like metformin and lifestyle changes.

The combination therapy improved PCOS symptoms in both obese and non-obese women, with weight loss in the obese group.

Minoxidil treatment increases aorta elasticity and reduces stiffness in aged mice, potentially helping with age-related heart issues.

An mFG score of 7 or higher indicates hirsutism in Filipino women, often linked to higher free testosterone levels.

New drugs and combination therapies are improving treatment for lower urinary tract symptoms.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Women with PCOS have higher levels of a certain growth factor, which can be reduced by taking metformin.

Premature hair graying may be a sign of increased risk for heart disease, indicating biological age is more important than actual age.

Measuring the distance from the anus to the clitoris may moderately help diagnose polycystic ovary syndrome, especially in certain cases.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

AMH is a good marker for diagnosing PCOS, but global standards are needed.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

Higher Lnk protein levels in ovaries may lead to insulin resistance in women with PCOS.