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Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Disrupted sleep patterns can harm skin and hair cell renewal, but melatonin might help.

Modified stem cells that overexpress a specific protein can improve hair growth and reduce hair abnormalities in mice.

BMP4-related anomalies can cause a wide range of eye, brain, and hand/foot problems, and new cases show this variability.

Keratin is crucial for keeping skin cells healthy and its changes can lead to diseases and affect cell behavior.

Testosterone is crucial for development, growth, and various body functions in mammals.

The analysis shows where minoxidil's atoms are likely to react and describes its electronic transitions and behavior with temperature changes.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

The E2 protein affects gene activity in hair follicles of mice.

VEGF helps squamous cell carcinoma grow in ways beyond just blood vessel formation.

Caffeic acid helps protect rats from the harmful effects of acrylamide.

Wild African goats have genetic adaptations for surviving harsh desert conditions.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

TLR3 signaling enhances the immunosuppressive properties of human periodontal ligament stem cells.

Some cancer and immune system drugs can cause serious side effects, including heart, lung, nerve, and organ damage, which need careful monitoring and management.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.