research PCSK9: From Nature's Loss to Patient's Gain
Certain genetic mutations can lower bad cholesterol and reduce heart disease risk, leading to effective cholesterol-lowering drugs.
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research Greasy Hair Against Obesity: TSLP-Induced Sebum Production Reduces Fat
Increasing sebum production might help reduce fat and improve metabolism.
research The Laboratory in the Multidisciplinary Diagnosis of Differences or Disorders of Sex Development (DSD)
Diagnosing sex development disorders requires combining medical history, physical exams, imaging, lab tests, and genetic data.
research Dietary Fat- and Obesity-Sensitive Dermal Adipocyte PKCβ Induction and Inflammation Cross-Talk
Eating a lot of fat increases PKCβ and inflammation in skin fat cells, which affects skin and hair health.
research Acne Vulgaris
Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.
research Is Lichen Planus a Marker for Dyslipidemia and Metabolic Syndrome?
Lichen planus may be associated with a higher risk of metabolic syndrome.
research Viewpoint 3
Oxidative stress plays a significant role in vitiligo, and both skin and non-skin cells may be involved.
research Cutaneous Androgen Metabolism: Basic Research And Clinical Perspectives
Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research Cutaneous Syndromes Produced as Side Effects of Triparanol Therapy
Triparanol therapy can cause hair loss and skin dryness without inflammation or damage to hair follicles or skin structures.
research Niosomes as a Promising Carrier for Topical Drug Delivery
Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
research Metformin Therapy for the Reproductive and Metabolic Consequences of Polycystic Ovary Syndrome
Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Sex Steroid Synthesis in Human Skin In Situ: The Roles of Aromatase and Steroidogenic Acute Regulatory Protein in the Homeostasis of Human Skin
Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
research Inactivation of Autophagy Leads to Changes in Sebaceous Gland Morphology and Function
Autophagy is crucial for normal sebaceous gland function and sebum composition.
research Metabolic and Pathologic Profiles of Human LSS Deficiency Recapitulated in Mice
Mice with LSS deficiency showed hair loss and cataracts, similar to humans, and can help in understanding and treating this condition.
research Prevention of Lipid Loss from Hair by Surface and Internal Modification
Surface and internal treatments can help prevent hair lipid loss during washing.
research Minoxidil Sulfotransferase, A Marker Of Human Keratinocyte Differentiation
Minoxidil sulfotransferase is a marker of keratinocyte differentiation and may play a role in hair growth.
research Flavonoids and Saponins: What Have We Got or Missed?
More high-quality research is needed to recommend flavonoids and saponins for clinical use.
research Exploration of Potential Lipid Biomarkers for Premature Canities by UPLC-QTOF-MS Analyses of Hair Follicle Roots
Researchers found that certain lipids, especially vitamin D3, are lower in prematurely grey hair than in pigmented hair.
research Testicular Steroidogenesis: Production and Regulation of Testosterone and Dihydrotestosterone
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Steroid Hormones: Overview and Medical Applications
Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
research Effects of Wet Cupping on Blood Components, Especially Skin-Related Parameters of Healthy Cases: A Case Control Metabonomic Study
Wet cupping blood has different components than regular venous blood, which might affect skin disorder treatments.
research Acanthosis Nigricans During HAIR-AN Syndrome: The Tree That Hides the Forest
The case shows skin changes can indicate deeper health issues like insulin resistance, which are challenging to manage.
research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
research Assessment on the Effects of Liposome-Encapsulated Thioglycolic Acid on Hair Perming
Liposome-encapsulated thioglycolic acid improves hair perming effectiveness and durability.
research Stromal Cells of the Human Postmenopausal Ovary Display a Distinctive Biochemical and Molecular Phenotype
Postmenopausal ovary stromal cells have a unique makeup and limited steroid production, suggesting androgens come from the adrenal gland.
research Insulin Resistance and Elevated Androgen Levels: A Major Cause of Polycystic Ovary Syndrome
Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.
research Healthy Tofu (Tofu Made From Almonds and Sunflower Seeds)
Almond and sunflower seed tofu is high in protein and marketed for diets and vegetarians.