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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Birth control pills increase certain receptor activities in female gerbil prostate glands and can lead to prostate changes.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Primary care is key in managing PCOS, focusing on lifestyle changes and medications like birth control and metformin.

Most female students at Qassim University know about PCOS, but there are still misunderstandings about it.

Hormonal changes and psychological issues can cause sexual dysfunction in postmenopausal women. Behavioral therapy is recommended first, with hormone replacement helping some symptoms but not libido. Testosterone can improve libido, but its effects on overall sexual function are unclear. Emotional and relationship issues should be addressed before using medication, and the benefits and risks of testosterone supplementation should be considered.

The document concludes that early recognition and treatment of PCOS in adolescents is crucial for managing symptoms and long-term health risks.

Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.

Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.

Hormonal contraceptives can help treat acne by affecting sebum production and androgen levels.

Dienogest combined with ethinylestradiol is a highly effective birth control that improves menstrual symptoms and has manageable side effects.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.

Birth control pills change the activity of certain inflammation and blood clotting genes in women with PCOS.

A transwoman developed a brain tumor after nine years of hormone therapy, suggesting a possible link between the treatment and tumor development.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

The levonorgestrel implant increases free testosterone and lowers SHBG more than DMPA-IM and the copper IUD.

Losing 5-10% body weight can improve PCOS symptoms, letrozole is better than clomiphene for fertility, and managing weight and blood sugar is important to reduce pregnancy complications.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.

Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.

Women with PCOS who had antiandrogenic treatment before pregnancy had fewer complications than those without treatment.

Testosterone therapy is beneficial for women's health and does not cause masculinization or liver damage, and it protects the heart and breasts.

Hormonal therapies are safe and effective for treating adult women's acne.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Adult female acne is a complex condition that can worsen with menopause, requiring holistic treatment and tailored skincare at different life stages.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

Adult female acne requires a comprehensive treatment approach, including medical options and lifestyle changes, with attention to psychological well-being.