January 2025 in “International Journal of Veterinary Science” In this animal study, hibiscus leaf simplicia ointment was found to protect red blood cell levels and promote better hair growth in UV-exposed rats, though it did not maintain normal skin histology; the ointment showed no significant acute dermal toxicity.
This study formulated and evaluated a Hibiscus rosa-sinensis herbal gel, identifying a 20% concentration as superior in physical properties, suggesting its potential as an alternative drug delivery system.
24 citations
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August 2018 in “Journal of Ayurvedic and herbal medicine” In this review, the authors summarize the phytochemistry, pharmacology, and medicinal uses of Hibiscus rosa sinensis, highlighting its various benefits such as hypotensive and anti-inflammatory effects, while noting the need for more research on its specific mechanisms and potential toxicities.
22 citations
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November 2016 in “Indian Journal of Pharmaceutical Education and Research” This study found that ethanolic leaves extract of Hibiscus rosa-sinensis L. exhibited strong antioxidant activity and enhanced wound healing properties in mice, showing reasonable safety in toxicological evaluations without severe alterations.
October 2023 in “Plant Archives/Plant archives” This study evaluated herbal formulations, including Neem and Hibiscus soaps and medicated oil, made from certain medicinal plants in India, finding them effective for antimicrobial purposes and beneficial for skin and hair, suggesting they are suitable for public use.
June 2025 in “Open Access Research Journal of Biology and Pharmacy” This study formulated an ointment using ethanolic extract from M. paradisiaca unripe peels and found that while the extract alone showed higher antibacterial activity against S. aureus and E. coli than the ointment, strategies to enhance the ointment's activity could be explored.
25 citations
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July 2017 in “Archives of Dermatological Research” This review summarizes preclinical and clinical information on herbal products for hair loss treatment, highlighting their mechanisms, follicular penetration, and potential side effects, suggesting they may offer alternatives to synthetic drugs with fewer side effects.
January 2026 in “Indus journal of bioscience research.” In this study, Hibiscus rosa-sinensis extract was used to formulate and evaluate herbal cosmetic creams for their antioxidant properties, stability, and effectiveness. The formulations demonstrated strong antioxidant potential, stability under various conditions, and favorable cosmetic qualities, suggesting HRS as a beneficial ingredient in skincare products.
January 2023 in “International Journal for Research in Applied Science and Engineering Technology” This review discusses the mechanism of "Malassezia" dandruff and the potential benefits of herbal treatments, focusing on phytoconstituents with anti-inflammatory, antibacterial, and antifungal properties, but reports no new experimental results.
July 2024 in “International Journal of Advanced Research in Science Communication and Technology” This study explored the antibacterial and wound-healing effects of an 80% methanol extract from Hibiscus micranthus leaves, finding it effective against several bacterial strains and beneficial for wound healing in rats.
January 2025 in “International Journal of Pharmaceutical Research and Applications” In this research, topical gels using natural mucilages from okra and hibiscus were successfully formulated to deliver diclofenac diethylamine, with hibiscus mucilage at 10% showing the best performance as a gelling agent based on various physicochemical tests.
19 citations
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January 2010 in “International Journal of Ayurveda Research” In this study, topical application of Tectona grandis seed extracts on albino mice significantly accelerated hair growth initiation time and increased the percentage of hair follicles in the anagenic phase compared to the standard minoxidil treatment.
5 citations
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April 2022 in “IntechOpen eBooks” This source describes the potential benefits of a nanoemulgel delivery system for enhancing the use of lipophilic drugs, improving patient compliance, and expanding treatment options for various conditions, including acne, arthritis-related inflammation, and Parkinson's disease, while also offering sunburn protection in cosmetic applications.
18 citations
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January 2007 in “Pharmaceutical Biology” This study found that petroleum ether extracts of Citrullus colocynthis reduced hair growth initiation time and advanced more hair follicles to the anagen phase in albino rats compared to untreated controls and minoxidil.
13 citations
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April 2019 in “American Journal of PharmTech Research” In this study, researchers highlighted that emulgels, a combination of emulsions and gels, offer a novel topical delivery method for hydrophobic drugs, possessing attributes such as easy spreadability and bio-friendliness, making them suitable for conditions like acne, fungal infections, and psoriasis.
1 citations
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January 2024 in “International Journal of Advanced Research in Science, Communication and Technology” This review article highlights the potential benefits of herbal remedies for hair loss, suggesting that formulating hair scrubs from herbal ingredients may effectively prevent and treat hair problems by improving self-confidence and self-esteem.
August 2023 in “International Ayurvedic medical journal” This case study describes the successful treatment of a 7-year-old girl with alopecia areata using Ayurvedic approaches targeting skin and autoimmune issues, suggesting a potential alternative to long-term oral corticosteroids, which can cause undesirable side effects.
December 2023 in “World Journal Of Advanced Research and Reviews” In this research, a chemical-free herbal hair mask was formulated and evaluated in the laboratory, aiming to strengthen hair follicles, remove dirt and dandruff, and darken hair color, with the goal of treating hair problems without adverse effects associated with synthetic products.
434 citations
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October 2003 in “PTR. Phytotherapy research/Phytotherapy research” This review discusses the use of natural products in cosmetic preparations for skin and hair care, but reports no new research results.
191 citations
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February 2002 in “Archives of Dermatology” This review discusses herbal therapies for dermatologic disorders, focusing on those with scientific evidence of efficacy and common interactions, but reports no new clinical results.
170 citations
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September 2019 in “Evidence-based Complementary and Alternative Medicine” This review discusses the use of 36 medicinal plant species for cutaneous wound healing and reports no new clinical results; the authors highlight the potential for these traditional practices to inform modern therapies.
41 citations
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July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
22 citations
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July 2017 in “BMC complementary and alternative medicine” This study documented the use of 41 plant species in the West Bank for treating hair and scalp disorders, highlighting their folkloric significance and potential for new cosmetic and cosmeceutical products.
16 citations
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September 2018 in “Journal of Ethnopharmacology” This review discusses the role of inheritance, androgens, and microinflammation in androgenetic alopecia and suggests some plant-based folk remedies may help address these factors but reports no new clinical results.
14 citations
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October 2020 in “Natural Products and Bioprospecting” This review discusses current topical treatments, natural products, and complementary therapies for androgenetic alopecia, but it reports no new clinical results.
9 citations
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March 2011 in “Oxidative stress and disease” This review explores herbal medications for skin disorders, covering their clinical efficacy, safety, and common drug interactions, but reports no new clinical results.
8 citations
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April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
6 citations
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February 2018 in “PLOS ONE” This study found that insect wax can significantly promote hair growth in mice in a way that is comparable to minoxidil, likely due to the upregulation of VEGF expression.
5 citations
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February 2011 in “Expert Opinion on Drug Discovery” This review discusses techniques and models for assessing hair growth activity but reports no new clinical findings, emphasizing the need for standardization and improved animal models.
4 citations
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October 2016 This source describes the potential of various herbal treatments, such as aloe vera and amla, as natural alternatives for managing hair loss and enhancing hair health, noting their benefits include fewer side effects, affordability, and multiple application methods.