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    Research 241–270 of 1000+

    1. Hh 2014
    2. Plakophilin 1 suppresses keratinocyte innate immune responses through DExD/H helicases 2026
    3. Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000 · 194 citations
    4. Hedgehog signalling in skin development and cancer Experimental Dermatology · 2006 · 190 citations
    5. Epidermal β-catenin activation remodels the dermis via paracrine signalling to distinct fibroblast lineages Nature Communications · 2016 · 115 citations
    6. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    7. Targeting of Smoothened for therapeutic gain Trends in Pharmacological Sciences · 2014 · 105 citations
    8. Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice Journal of Investigative Dermatology · 2011 · 100 citations
    9. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    10. Targeting Superficial or Nodular Basal Cell Carcinoma with Topically Formulated Small Molecule Inhibitor of Smoothened Clinical cancer research · 2011 · 63 citations
    11. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    12. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma Nature Communications · 2020 · 60 citations
    13. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    14. GLI2-specific Transcriptional Activation of the Bone Morphogenetic Protein/Activin Antagonist Follistatin in Human Epidermal Cells 2008 · 39 citations
    15. From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots British Journal of Dermatology · 2017 · 17 citations
    16. Mommy — where do tumors come from? 2011 · 16 citations
    17. Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road Journal of Investigative Dermatology · 2014 · 15 citations
    18. Basal cell carcinomas acquire secondary mutations to overcome dormancy and progress from microscopic to macroscopic disease Cell Reports · 2022 · 14 citations
    19. DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice Journal of Investigative Dermatology · 2014 · 11 citations
    20. The Organizer and Beyond Cell · 2001 · 9 citations
    21. Skin Deep and Deeper: Multiple Pathways in Basal Cell Carcinogenesis Cancer Prevention Research · 2010 · 5 citations
    22. Regulation of stem cell fate by HSPGs: implication in hair follicle cycling npj Regenerative Medicine · 2022 · 3 citations
    23. Molecular mechanisms of ectodermal dysplasia syndromes Työväentutkimus Vuosikirja · 2004 · 3 citations
    24. Dermal Hedgehog Signaling in Papillary Fibroblasts: An Emerging Key Player in Skin Regeneration Journal of Investigative Dermatology · 2022 · 2 citations
    25. 139 Anti-BCC efficacy of a topical hedgehog inhibitor without adverse effects in BCNS patients in a phase 2 randomized controlled trial 2018 · 1 citations
    26. Understanding Cancer Cells of Origin in Cutaneous Tumors Elsevier eBooks · 2016 · 1 citations
    27. Modulating embryonic signaling pathways paves the way for regeneration in wound healing Frontiers in physiology · 2024
    28. Dermal β-Catenin Is Required for Hedgehog-Driven Hair Follicle Neogenesis. 2024
    29. The HEDGEHOG-GLI1 pathway is important for fibroproliferative properties in keloids and as a candidate therapeutic target Communications biology · 2023
    30. Keloid pathogenesis and fibroproliferative properties are dependent on stem cells regulated by the HEDGEHOG-GLI1 pathway Research Square (Research Square) · 2023