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Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

New compounds may soon be tested to treat excessive hair growth in women.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

A new compound effectively inhibits human 5α-reductase 1.

New tests detect finasteride and dutasteride in urine quickly and easily.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.

Certain drugs that block specific enzymes can help treat prostate diseases.

Rosemary extracts with carnosic acid and carnosol can reduce the harmfulness of Staphylococcus aureus without stopping its growth.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

A new compound shows promise as a topical treatment for hair loss.

New regenerative treatments for hair loss show promise but need more research for confirmation.

Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.

A new method quickly detects hair changes from EGFR inhibitors using a microscope.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

A new mutation in the STING protein causes a range of symptoms and its severity may be affected by other genetic variations; treatment with a specific inhibitor showed improvement in one patient.

Some leukemia treatments can cause skin reactions similar to keratosis pilaris.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

Blocking the Mitochondrial Pyruvate Carrier causes stress in hair follicles, which can be reduced by an ISR inhibitor.

CD8+ T cells are involved in alopecia areata and may cause disease relapse.

Different drugs for prostate-related urinary symptoms work but have various side effects, and treatment should be tailored to the individual.

A patch made from human lung fibroblast material helps heal skin wounds effectively, including diabetic ulcers.

Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.

Phospholipase A2 is necessary for the correct placement of PIN proteins in plant roots, affecting root growth.

RANK is a key target in breast cancer treatment due to its role in tumor growth and bone metastasis.

GLI2 increases follistatin production in human skin cells.