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Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.

Targeted therapy for skin cancer is complex due to the role of the hedgehog pathway in both cancer and hair growth.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

Skin needs dermal β-catenin activity for hair growth and skin cell multiplication.

The hedgehog signaling pathway is crucial for hair growth but not for the initial creation of hair follicles.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Scientists found a new, less invasive way to study body clocks using hair cells, which shows shift workers' body clocks don't match their lifestyles.

Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.

Tumor suppressors help control inflammation in cancer and restoring their function could lead to new treatments.

Placental growth factor may help treat hair loss.

ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.

Rats can't grow new hair follicles after skin wounds, unlike mice, due to differences in gene expression and response to WNT signaling.

A newly found RNA in Cashmere goats may play a role in hair growth and development.

The article concludes that hair loss is a common side effect of drugs treating skin cancer by blocking the hedgehog pathway, but treatment should continue, and more selective drugs might prevent this side effect.

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

Cells from certain embryo parts can induce head formation in another embryo, involving complex signaling pathways.

Ferrous Ferric Chloride may improve skin cell function and increase hair growth in mice.

Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.

Hair follicle samples effectively show how well the drug MK-0752 targets and engages with the Notch pathway.

Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

Helminth protein helps wounds heal better by reducing scarring and promoting tissue growth.

Phloroglucinol may help improve hair loss by promoting hair growth and reducing oxidative stress.

Modifying certain signals in the body can help wounds heal without scars and regrow hair.

The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.

New research has found 14 genes linked to the risk of developing alopecia areata, improving understanding and treatment options.

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

Skin health and repair depend on the signals between skin stem cells and their surrounding cells.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.