38 citations
,
November 2018 in “Scientific Reports” This study suggests that chicken and alligator scales evolved independently through convergent evolution rather than sharing a common origin with avian feathers.
9 citations
,
February 1996 in “Lancet” In this study, reversible ageusia in a patient was strongly suggested to be caused by losartan, with potential implications for angiotensin receptor involvement in taste disturbance.
1 citations
,
July 2025 in “Cancer Medicine” This study observed that colorectal cancer tumoroids adapted to an environment without a matrix by developing disordered self-assembly, but their tumor-specific phenotypes and drug sensitivity remained unchanged.
May 2023 in “BMC Women's Health” This study found that female patients in Finnish specialized health care with a history of doping use exhibited high rates of psychiatric and substance use disorder morbidity, with less than half of those using anabolic androgenic steroids showing atypical red blood cell parameters.
This study found that human growth hormone encapsulated in nano-liposome increased the number of hairs and stimulated hair cycling in mice, suggesting potential benefits for addressing hair loss.
215 citations
,
September 2003 in “Journal of Biological Chemistry” This study found that the hairless gene product (Hr) suppresses VDR-mediated gene activation by directly interacting with the vitamin D receptor, potentially affecting hair follicle function.
47 citations
,
April 2000 in “The American journal of pathology” This study found that overexpressing human Bcl-2 in mice protected epidermal keratinocytes from UVB-induced apoptosis but unexpectedly increased apoptosis during hair follicle regression and chemotherapy.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
40 citations
,
May 2005 in “Journal of Cell Science” In this study, transgenic mice expressing a truncated form of latent transforming growth factor-β-binding protein exhibited altered hair cycles due to increased active transforming growth factor-β, impacting keratinocyte proliferation and hair cycle phases.
31 citations
,
May 2021 in “Journal of endocrinological investigation” This study in Italy found that APS-1, a rare disorder, is associated with various AIRE gene mutations and most individuals have autoantibodies such as IFNωAbs, which are markers of the condition.
30 citations
,
November 2024 in “ACS Materials Au” This article provides an overview of microneedle technology for transcutaneous drug delivery, discussing microneedle designs, materials, and activation methods that enhance drug stability and regulated release, and outlines considerations for their successful clinical implementation, such as biocompatibility and production cost.
28 citations
,
April 2021 in “Biomedicines” This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.
22 citations
,
November 2023 in “Molecules” This review focuses on recent advances in smart responsive polymer microneedles, which offer precise, on-demand drug delivery triggered by external or physiological stimuli, highlighting significant research implications for transdermal drug administration according to this source.
21 citations
,
September 2003 in “Journal of Clinical Investigation” This paper reports that noggin inhibits BMP-2 and BMP-4 functions by binding and blocking their interaction with the BMP receptor, impacting multiple developmental processes without presenting new research results.
13 citations
,
October 2019 in “Oncology Reports” This review discusses the complex relationship between anabolic substances and colorectal cancer risk, reporting ambiguous findings on their carcinogenic properties, potential synergy with risk factors, and protective roles.
12 citations
,
July 2017 in “Annals of saudi medicine/Annals of Saudi medicine” This study found widespread use of performance enhancing agents among gym users in Saudi Arabia and suggests that improving knowledge and awareness could reduce consumption despite accessibility and social influences.
9 citations
,
September 2019 in “PLoS ONE” This study demonstrated that keratin K124 is specific to equine hoof lamellar tissue and established monoclonal antibodies that can specifically recognize K124 without cross-reacting with other tissues.
8 citations
,
January 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” This review discusses how neuroendocrine regulation affects human hair follicles and suggests potential therapeutic targets, but it reports no new clinical results.
8 citations
,
February 2022 in “PLoS ONE” This study found that Bacillus subtilis strain Ydj3 significantly enhanced sweet pepper seed germination, fruit quality, and rhizosphere bacterial composition, including increased yield and vitamin C content, in a commercial greenhouse setting.
4 citations
,
December 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” This article discusses the role of human scalp hair follicles in neurohormone production and their model potential for studying neuroendocrine signaling, reporting no experimental results.
2 citations
,
November 2025 in “Cells” This review presents evidence supporting the potential of adipose-derived stem cell secretome as a promising cell-free therapy for skin repair, emphasizing its application in wound healing, alopecia, skin rejuvenation, and inflammatory skin diseases.
2 citations
,
August 2025 in “Harm Reduction Journal” This study highlights the severe health risks and dependence associated with non-medical androgen use among gym-goers, stressing the need for specialized primary care and harm-reduction strategies due to potentially fatal outcomes even after prolonged cessation.
2 citations
,
July 2025 in “Forensic Sciences” This review concludes that anabolic–androgenic steroid abuse may lead to significant neurotoxicity, affecting brain structure, neurotransmitter systems, and increasing the risk of mood disorders and cognitive deficits.
1 citations
,
February 2023 in “Applied sciences” This study found that methylcellulose-based hydrogels can effectively deliver growth hormone through the skin, with albumin increasing the hormone's permeation to 93% in simulated in vivo conditions.
August 2025 in “MedComm – Biomaterials and Applications” This review highlights recent advances in liposome-based transdermal drug delivery systems, emphasizing their potential to improve drug penetration for both skin and systemic diseases while discussing the challenges and future directions in this field.
November 2024 in “Applied Sciences” This study suggests that while some evidence indicates potential efficacy of placental products for hair growth and inhibiting hair loss, the current scientific evidence is scarce and of low quality.
April 2023 in “Clinical Chemistry and Laboratory Medicine” The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.
April 2020 in “BMC endocrine disorders” This case report describes a 65-year-old woman with childhood-onset growth hormone deficiency who developed panhypopituitarism, including late-onset secondary hypoadrenocorticism, affecting her respiratory and renal function.
11 citations
,
December 1987 in “Aesthetic Plastic Surgery” This article discusses the role of suction-assisted lipectomy (SAL) and the hCG method in obesity management, highlighting the speculative benefits of hCG but reporting no new clinical findings.
9 citations
,
October 1976 in “Journal of Cutaneous Pathology” This study observed that human growth hormone treatment in osteoporosis patients appeared to improve skin thickness and restore dermal structures towards normal without stimulating hair, sebum, or melanin.