research The Anti-Apoptotic Bcl-2 Protein Regulates Hair Follicle Stem Cell Function
The Bcl-2 protein is important for keeping hair follicle stem cells working and preventing hair loss.
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research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Investigating the Mechanisms Underlying Age-Related Dysfunctions in Skin and Hair Follicle Regeneration
research Faculty Opinions Recommendation of Identification of Functional Patterns of Androgenetic Alopecia Using Transcriptome Profiling in Distinct Locations of Hair Follicles
research Normal Stem Cells and Cancer Stem Cells: Similar and Different
Deregulation of stem cell function is central to the development of some cancers.
research Immune Privilege Collapse And Alopecia Development: Is Stress A Factor
Stress may trigger hair loss by affecting immune protection in hair follicles.
research Progenitor Cell Dysfunctions Underlie Some Diabetic Complications
Diabetes causes lasting cell dysfunctions, leading to serious complications even after blood sugar is controlled.
research Expression of the Orphan Protein Plet-1 During Trichilemmal Differentiation of Anagen Hair Follicles
Plet-1 protein helps hair follicle cells move and stick to tissues.
research Generation of Skin Organoids: Potential Opportunities and Challenges
Skin organoids from stem cells could better mimic real skin but face challenges.
research Transdifferentiation of Human Hair Follicle Mesenchymal Stem Cells into Red Blood Cells by OCT4
Human hair follicle stem cells can be turned into red blood cells.
research Characterization of the Epidermal-Dermal Junction in hiPSC-Derived Skin Organoids
The study created hair-bearing skin models that lack a key protein for skin layer attachment, limiting their use for certain skin disease research.
research Argan (Argania Spinosa) Press Cake Extract Enhances Cell Proliferation and Prevents Oxidative Stress and Inflammation of Human Dermal Papilla Cells
Argan press cake extract might help grow hair and protect hair cells from damage and inflammation.
research Pharmacological Mobilization of Endogenous Bone Marrow Stem Cells Promotes Liver Regeneration After Extensive Liver Resection in Rats
Using a drug to activate bone marrow stem cells can help the liver regenerate and function better after major surgery in rats.
research Hair Loss Caused by Gain-of-Function Mutant TRPV3 Is Associated with Premature Differentiation of Follicular Keratinocytes
A gene mutation causes early keratinocyte maturation leading to hair loss in Olmsted syndrome.
research Biofabrication of Human Skin with Its Appendages
Current methods can't fully recreate skin and its features, and more research is needed for clinical use.
research Different Synaptic Stimulation Patterns Influence Local Androgenic and Estrogenic Neurosteroid Availability Triggering Hippocampal Synaptic Plasticity in Male Rats
The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.
research Pharmaceutical Nanotechnology in Egypt: Diverse Applications and Promising Outcomes
Egyptian researchers are advancing in pharmaceutical nanotechnology, potentially improving health outcomes and the economy.
research Comprehensive Transcriptome Analysis of Hair Follicle Morphogenesis Reveals That lncRNA-H19 Promotes Dermal Papilla Cell Proliferation Through the Chi-miR-214-3p/Beta-Catenin Axis in Cashmere Goats
The research found that the molecule lncRNA-H19 helps hair follicle cells grow by affecting certain cell pathways in cashmere goats.
research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Stem Cell Niches
Stem cell niches regulate the number and function of stem cells in the body.
research Editorial: Hair Follicle Stem Cell Regeneration in Aging
Aging causes hair loss and graying due to stem cell decline and changes in cell behavior and communication.
research The Long Road Traveled in Hematopoietic Stem Cell Gene Therapy
The FDA approved the first gene therapy for a blood disorder after overcoming early challenges and demonstrating patient benefits.
research Vitamins and Their Derivatives Synergistically Promote Hair Shaft Elongation via PlGF/VEGFR-1 Signalling Activation
Certain vitamins and their derivatives can help hair grow longer by activating specific growth signals.
research MicroRNA-148a Controls Epidermal and Hair Follicle Stem/Progenitor Cells by Modulating the Activities of ROCK1 and ELF5
MicroRNA-148a is crucial for maintaining healthy skin and hair growth by affecting stem cell functions.
research Intrinsic and Extrinsic Factors Associated with Hair Graying and Therapeutic Potential of Plant Extracts and Phytochemicals
Plant extracts may help prevent or reverse hair graying.
research Evaluation of the Effects of Adding an Adipose Tissue-Derived Stromal Vascular Fraction to Platelet-Rich Plasma Injection in the Treatment of Androgenetic Alopecia: A Randomized Clinical Trial
Adding stromal vascular fraction to platelet-rich plasma injections did not significantly improve hair growth in androgenetic alopecia treatment.
research Minoxidil Delivered Via a Stem Cell Membrane Delivery Controlled Release System Promotes Hair Growth in C57BL/6J Mice
A new method using stem cell membranes to deliver Minoxidil improved hair growth in mice better than Minoxidil alone.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack
Hair follicles prevent NK cell attacks to avoid hair loss.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.