Skin stem cells are crucial for maintaining and repairing skin, with potential for treating skin disorders and improving wound healing.
August 2016 in “Journal of Investigative Dermatology” DHT reduces a cell's ability to promote hair growth, while 3D culture without DHT improves it.
The modified stem cells with VEGF165 in a special scaffold improved blood vessel growth and wound healing for skin repair.
November 2022 in “Journal of Investigative Dermatology” Occipital hair follicles in male pattern baldness respond uniquely to testosterone, not androgen-insensitive.
April 2023 in “ACS Biomaterials Science & Engineering” 3D scaffolds mimicking the extracellular matrix are crucial for effective hair follicle regeneration.
February 2023 in “International Journal of Molecular Sciences” Exosomes from skin cells can boost hair growth by stimulating a gene called LEF1.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
January 2023 in “Dermatology” Ageing and increased senescent cells significantly contribute to common hair loss.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
30 citations,
November 2018 in “EMBO Reports” The Ovol2-Zeb1 circuit is crucial for skin healing and hair growth by guiding cell movement and growth.
5 citations,
February 2013 in “Dermatology and therapy” Crescina® lotion helps reduce hair loss and increase hair growth in males with androgenetic alopecia.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
November 2022 in “Journal of Investigative Dermatology” Minoxidil and PRP can help convert miniaturized hair follicles back to normal in male pattern baldness.
November 2022 in “Journal of Investigative Dermatology” Growth hormone-releasing hormone (GHRH) boosts hair growth and human scalp hair follicles have their own growth hormone system.
November 2022 in “Journal of Investigative Dermatology” Butyrate helps hair grow longer, improves hair cell health, increases pigment production, and boosts hair's natural defenses.
September 2016 in “Journal of dermatological science” Human induced pluripotent stem cells can be used to create cells that help grow hair.
September 2022 in “Journal of Theoretical Biology” Hair follicles can regenerate after radiation damage but not during a specific growth phase.
92 citations,
September 2013 in “Journal of Investigative Dermatology” BMAL1 and Period1 genes can influence human hair growth.
71 citations,
May 2007 in “The FASEB journal” Human hair follicles produce and respond to erythropoietin, helping protect against stress.
Activating certain cells in hair follicles can prevent hair loss caused by cancer treatments.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
January 2022 in “SSRN Electronic Journal” Mouse hair follicles age, causing more white hairs due to fewer pigment stem cells.
September 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair follicles repair 3D injuries using a 2D healing process.
33 citations,
January 2018 in “Blood” Ruxolitinib helps protect skin stem cells and keeps skin healthy in mice with skin GVHD.
18 citations,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
7 citations,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
September 2024 in “Journal of the American Academy of Dermatology” Estetrol (E4) may help treat female pattern hair loss by prolonging hair growth.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Electrical epilation damages hair follicles and surrounding skin, likely preventing hair regrowth.