Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

Hemp seed biomaterials may reduce hair loss and improve hair growth.

This study demonstrated that tight junction barriers exist in human hair follicles but are less tight in hair follicle keratinocytes than in interfollicular keratinocytes, highlighting claudin-1's key role in follicle barrier function and growth.

In this study, chronic exposure to finasteride induced metabolic disturbances and depression-like behaviors in young male rats, similar to those caused by obesity, but did not worsen anxiety or depression in obese rats.

This study found that the Dongeui Hot Spring Water complex (Dongui Hot Spring Water CPX), containing sea slug extract and panthenol, demonstrated higher antioxidant activity and cell proliferation, suggesting potential benefits for preventing hair loss and improving scalp health.

In laboratory conditions, this study found that the Dongeui Hot Spring Water Complex, containing sea slug extract, demonstrated enhanced antioxidant activity and promoted hair papilla cell proliferation compared to a control, suggesting potential benefits for scalp health and hair loss prevention.

In this study, researchers linked SARS-CoV-2 infection to telogen effluvium in some COVID-19 patients by observing the accumulation of viral proteins in hair follicle cells, which may trigger stress responses and cell death, suggesting hair follicles as a potential target in COVID-19.

This study observed that minoxidil induced myocardial necroses and hemorrhages in beagle dogs and miniature swine, with greater severity seen in dogs.

This study suggests that sinapic acid may promote hair growth in human hair follicle dermal papilla cells by activating specific signaling pathways and inducing the expression of growth factors.

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

This study found that adipose-derived mesenchymal stem cells from type 2 diabetes mice were slightly less effective, yet had comparable therapeutic effects on wound healing compared to non-diabetic controls.

This review critically analyzes recent literature on the use of nanotechnology in alopecia treatment, reporting promising results for improving drug delivery and hair growth, though challenges in maintaining physical stability may limit large-scale commercialization.

This study suggests that hair follicle dermal stem/progenitor cells play a key role in both hair regeneration and skin wound healing, with potential implications for preventing hair follicle miniaturization linked to aging or alopecia.

This study found that surface modified nanoparticles showed increased skin permeation and improvement in allergic contact dermatitis, independent of the follicular pathway.

This study developed a new human hair research model combining 3D spheroid dermal papilla fibroblasts with plucked anagen hair shafts, potentially improving the evaluation of hair follicle differentiation.

This study found that dihydrotestosterone induced hair loss and changes in hair morphology in male C57BL/6 mice, effects that could be partially reversed by the AR antagonist bicalutamide.

This study found that Hoxc13 gene expression, influenced by melatonin, was associated with hair follicle activity in Cashmere goats, with in vitro evidence suggesting effects on genes relevant to follicle development.

This paper reviews the role of pharmacokinetic/pharmacodynamic modeling in drug development, emphasizing its application for drug dosing guidance, safety resolution, and therapeutic monitoring improvement, without presenting new clinical results.

This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.

This article discusses the development and testing of comprehensible over-the-counter drug product labels, highlighting the need for improved consumer understanding and calling for further research on label design.

This study demonstrated that the biomimetic peptide PTP20 may help preserve hair pigmentation and reduce greying by enhancing melanocyte function and increasing melanin production in human hair follicles.

In this study, the methanol-ultrasound extract of Dendropanax morbifera leaf showed potential for use in functional cosmetics and hair growth products due to its high antioxidant capacity and effects on growth factor expression without cytotoxicity.

This study found that platelet-rich plasma injections promote hair growth and are safe and effective for treating androgenetic alopecia.

This study introduced Cadd4, a peptide-based degrader developed using computer-aided drug design, which effectively reduced PCSK9 levels and increased LDL receptor expression, resulting in decreased plasma cholesterol and LDL-C levels in hypercholesterolemic mice, without liver toxicity.

This review discusses the isolation, characterization, and potential clinical applications of tissue-derived extracellular vesicles in cancer diagnosis, prognosis, and treatment, noting their significance but highlighting the risks and need for appropriate protocols.

In this study, finasteride improved cardiac sympathovagal balance in aging and obese male rats, also enhancing left ventricular function specifically in those modeled for aging, but not affecting healthy rats.

This study observed that topical application of maslinic acid stimulated hair growth in mice comparably to minoxidil, possibly through the Wnt/β-catenin pathway and involving ciliary gene activity, highlighting increased levels of trichogenic gene expression and protein levels.

This study found that extracts from Cirsium japonicum var. spinossimum seeds are rich in polyphenols and flavonoids, demonstrating significant anti-inflammatory and cell proliferation effects in specific cell models, suggesting potential as a source for anti-inflammatory and anticancer agents.

In this study, researchers found that while applying a lotion containing Lactiplantibacillus plantarum subsp. plantarum N793 did not improve hair density overall compared to placebo, it was effective in improving hair density among individuals with relatively mild hair thinning.

This study found that in mice, oral administration of Lactilactobacillus curvatus LB-P9 accelerated hair regrowth and increased hair thickness, hair follicle numbers, and dermal thickness, likely by boosting hair growth factor production and dermal papilla proliferation.

This study found that macrophages near hair follicles contribute to the activation of skin epithelial stem cells in mice, suggesting a novel role for macrophages in regulating hair growth.