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Skin stem cells in hair follicles are important for touch sensation.

Hair follicle stem cells are crucial for touch sensation and proper nerve structure in mice.

The drugs finasteride and dutasteride reduce low-grade prostate cancers but may double the risk of high-grade cancers.

Drinking a lot of alcohol increases the risk of prostate cancer and can worsen the condition.

Dutasteride effectively treats benign prostatic obstruction, improves urinary flow, reduces prostate size, and may prevent prostate cancer, but can cause sexual side effects.

Case-only trees and random forests improve predictions of treatment effects in clinical trials.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Drugs for hormone-related conditions might help treat mental disorders but could have serious side effects.

The review concludes that more research is needed to better improve the health outcomes for people with Polycystic Ovarian Syndrome.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Studying premature aging syndromes helps understand human aging and suggests potential treatments.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Microneedle patches improve drug delivery for skin treatments and cosmetic enhancements.

Liposomes show promise for delivering CRISPR for gene editing but face challenges like delivery efficiency and safety concerns.

miRNA-based therapies show promise for treating skin diseases, including hair loss, in animals.

A specific gene change plus an additional mutation in the same gene cause hereditary trichilemmal cysts.

Mutations in the enzyme don't significantly change how it binds to its specific substances.

FP-1 is a key protein in rat hair growth, active only during the growth phase.

Polysaccharides have many health benefits and are used in drugs, but isolating and purifying them is complex and requires careful methods.

Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

MicroRNAs could be key biomarkers and therapeutic targets for PCOS.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.

Increasing EGR1 levels makes hair root cells grow faster.