September 2019 in “Journal of Investigative Dermatology” BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
April 2024 in “Communications biology” Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.
4 citations,
January 2011 in “Cell stem cell” Hair follicle stem cells can return to their original niche and help regenerate hair.
2 citations,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
May 2023 in “Frontiers in Cell and Developmental Biology” The document concludes that using stem cells to regenerate hair follicles could be a promising treatment for hair loss, but there are still challenges to overcome before it can be used clinically.
4 citations,
January 2018 in “Microscopy research” Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
103 citations,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
57 citations,
April 2009 in “Differentiation” SDF-1/CXCL12 and its receptor CXCR4 are crucial for melanocyte movement in mouse hair follicles.
January 2018 in “Stem cell biology and regenerative medicine” ATP-dependent chromatin remodeling is crucial for skin development and stem cell function.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing Lrig1-positive stem cells in mice causes temporary loss of sebaceous glands.
March 2024 in “Journal of functional foods” Collagen peptides from marine and bovine sources may help prevent hair loss by affecting hair follicle stem cells differently.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
89 citations,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
Dermal stem cells help regenerate hair follicles and heal skin wounds.
June 2022 in “Research Square (Research Square)” Nestin-expressing cells turn into a specific type of skin cell in hair follicles during development and in adults.
43 citations,
December 2008 in “Molecular biology of the cell” Disrupting Smad4 in mouse skin causes early hair follicle stem cell activity that leads to their eventual depletion.
8 citations,
May 2021 in “Bioengineering & translational medicine” Hair growth environment recreated with challenges; stem cells make successful skin organoids.
January 2025 in “Cellular and Molecular Life Sciences” BMP4 helps stem cells turn into pigment-producing cells, affecting hair color and growth.
New treatments for hair loss, including a compound called "ALRV5XR", platelet-rich plasma, and Adult Stem Cell-based therapy, are showing promise, but more trials are needed for confirmation.
168 citations,
August 2009 in “EMBO molecular medicine” Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
4 citations,
January 2021 in “Cell transplantation” Scientists found the best time to transplant human stem cells for hair growth is between days 16-18 when they have the right markers and growth potential.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Linalool in personal care products may contribute to hair loss by damaging hair follicle stem cells and triggering harmful immune responses.
62 citations,
November 2009 in “Aging Cell” Hedgehog signaling helps keep hair follicle stem cells the same in both young and old human skin.
Linalool in personal care products may worsen frontal fibrosing alopecia by damaging hair follicle stem cells and triggering harmful immune responses.
April 2023 in “Journal of Investigative Dermatology” Being allergic to linalool, a common fragrance ingredient, might contribute to developing frontal fibrosing alopecia.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
1 citations,
March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
18 citations,
November 2020 in “Frontiers in Cell and Developmental Biology” Inflammation plays a key role in activating skin stem cells for hair growth and wound healing, but more research is needed to understand how it directs cell behavior.
117 citations,
March 2017 in “Nature Communications” Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.