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Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Normal skin cell renewal doesn't need RAR signaling, but vitamin A-related skin thickening does.

Fat cells in the skin help start healing and form important repair cells after injury.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

Eclipta alba extract may help hair grow similarly to Minoxidil.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Fetal wound healing changes with development, affecting inflammation and collagen, which may influence scarring.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Androgens can both stimulate and cause hair loss, and understanding their effects is key to treating hair disorders.

A WNT10A gene mutation leads to ectodermal dysplasia by disrupting cell growth and differentiation.

Drosha and Dicer are essential for hair follicle health and preventing DNA damage in skin cells.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Advanced human skin models improve drug development and could replace animal testing.

Cyclosporine A may help treat hair loss by blocking a protein that inhibits hair growth.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

Stem cells help repair tissue mainly by releasing beneficial substances, not by replacing damaged cells.

The control system for hair growth cycles is not well understood and needs more research.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Modified rat stem cells on a special scaffold improved blood vessel formation and wound healing in skin substitutes.

Botulinum toxin has potential for treating various skin conditions and improving wound healing.

FAGA diagnosis uses blood tests and trichoscopy, with treatments like topical minoxidil, oral anti-androgens, and hormone-modulating drugs.