17 citations,
December 2019 in “Stem Cells International” Bioactive molecules show promise for improving skin repair and regeneration by overcoming current challenges with further research.
26 citations,
December 2016 in “Pharmacology & Therapeutics” New drugs for heart disease may be developed from molecules secreted by stem cells.
December 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” MicroRNA-205 helps hair grow by changing the stiffness and contraction of hair follicle cells.
3 citations,
January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
174 citations,
November 2016 in “Cell stem cell” Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.
18 citations,
December 2018 in “Expert Opinion on Biological Therapy” Hair follicle stem cells are promising for wound healing but require more research for safe clinical use.
109 citations,
December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
69 citations,
April 2019 in “Biomedicines” PRP and HF-MSCs treatment improves hair growth, thickness, and density in androgenetic alopecia.
7 citations,
January 2022 in “Biomedicines” Cells from the lower part of hair follicles are a promising, less invasive option for immune system therapies.
January 2025 in “Journal of Cosmetic Dermatology” Exosomes are important for skin treatments and hair growth but need more research for safe and effective use.
53 citations,
April 2016 in “Stem cell research & therapy” LL-37 helps stem cells grow and move, aiding tissue regeneration and hair growth.
20 citations,
June 2020 in “Stem Cell Research & Therapy” Using stem cells from fat tissue can significantly improve wound healing in dogs.
1 citations,
December 2022 in “Parasitologists United Journal” House fly larvae substances improve wound healing and skin regeneration, especially in immunosuppressed mice.
6 citations,
January 2023 in “npj regenerative medicine” Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.
13 citations,
December 2014 in “Stem Cells” Hair and skin can regenerate without bulge stem cells due to other compensating cells.
23 citations,
September 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” NF-κB is crucial for different stages and types of hair growth in mice.
8 citations,
January 2022 in “Burns and trauma” Skin cell-derived vesicles can help heal skin injuries effectively.
4 citations,
March 2022 in “Pharmaceutics” Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
4 citations,
June 2022 in “BioMed Research International” Using mesenchymal stem cells or their exosomes is safe for COVID-19 patients and helps improve lung healing and oxygen levels.
61 citations,
June 2014 in “Scientific Reports” Wnt1a-conditioned medium from stem cells helps activate cells important for hair growth and can promote hair regrowth.
75 citations,
January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
24 citations,
September 2019 in “Experimental cell research” BMP2 helps hair follicle stem cells become specialized by increasing PTEN, which causes autophagy.
July 2024 in “Journal of Investigative Dermatology” TGF-β signaling is essential for new hair growth after a wound.
January 2025 in “Burns & Trauma” Skin organoids help improve wound healing and tissue repair.
479 citations,
January 2005 in “BioEssays” Hair follicle development is controlled by interactions between skin tissues and specific molecular signals.
46 citations,
June 2015 in “Journal of Investigative Dermatology” Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.
110 citations,
April 2020 in “Advances in Wound Care” Nanotechnology shows promise for better chronic wound healing but needs more research.
3 citations,
July 2023 in “International journal of molecular sciences” Stress may contribute to hair loss in alopecia areata by affecting immune responses and cell death in hair follicles.
41 citations,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
August 2016 in “Journal of Investigative Dermatology” The enzyme CD73 helps control human hair growth and could be targeted to treat hair growth disorders.