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This study found that both human and rat dermal papilla spheroids can induce hair follicle neogenesis, but larger spheroids increase inductivity without significantly affecting hair fiber diameter.

This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.

Results are not reported in this abstract, which outlines research investigating why diabetic mice experience suppressed hair follicle stem cell activation, potentially contributing to chronic diabetic wounds.

This study found that blocking apoptosis during the catagen phase in mice disrupts hair follicle stem cell niche architecture, delaying subsequent hair regeneration cycles.

This study found that hair follicle and interfollicular epidermis stem cells contribute differently to skin regeneration, with their persistence influenced by factors like spatial constraints and competition moderated by Notch suppression.

This study found that overexpression of the anti-apoptotic protein Bcl-2 in mice disrupted cell death during the hair cycle, impairing hair regeneration by delaying anagen entry and hair growth.

This study found that dermal papilla cell-derived exosomes promote hair follicle regeneration during wound healing by enhancing fibroblast activity and activating the Wnt/β-catenin signaling pathway in mice.

This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.

This review highlights the importance of using 3D scaffolds in vitro to support hair follicle regeneration, emphasizing how these structures help maintain cell function and mimic the natural environment, which is crucial for developing hair follicle organoids for transplantation.

This review discusses the potential of human induced pluripotent stem cells for regenerating hair follicles and developing cell-based therapies for hair loss, but it reports no new clinical results.

The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.

Scientists used a special imaging technique to observe that hair follicle regeneration involves cell division and structural changes, mostly in the lower part of the follicle, and that the dermal papilla at the base is crucial for regrowth.

This study found that human embryonic and induced pluripotent stem cells differentiated into specific bulge stem cells and successfully formed new hair follicles when transplanted with mouse dermal cells in immunodeficient mice.

This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.

This abstract omits specific findings and does not provide new research results.

This review explores the role of hair follicle dermal stem cells in skin regeneration and restorative therapies, but it reports no new experimental results.

This study suggests that interfollicular epidermal keratinocytes with stem-like features may serve as an alternative to follicular keratinocytes for hair regeneration by supporting hair follicle morphogenesis in vivo.

This study found that hair follicles across mouse skin form a heterogeneous regenerative field, with distinct cycling dynamics influenced by the balance of activator and inhibitor signals, which could inform other organ regeneration research.

Taxane chemotherapy can cause permanent hair loss by damaging hair follicles and altering their DNA.

In this review, the authors discussed how the circadian clock influences hair follicle regeneration by regulating metabolism, suggesting potential new targets for hair loss treatments.

In this study using a mouse model, researchers found that expressing Lef1 in dermal fibroblasts may enhance skin regeneration without affecting normal development.

This review outlines the transition from simple hair follicle organoids to immune-competent microphysiological systems, addressing limitations in replicating native hair follicle immune features and discussing their applications in disease modeling and regenerative medicine.

This study found that PBX1 overexpression reduces hair follicle-derived mesenchymal stem cell senescence and apoptosis by alleviating ROS-mediated DNA damage, rather than enhancing DNA repair.

This study found that PBX1 enhances the proliferation and reprogramming of hair follicle mesenchymal stem cells by activating the AKT/GSK3β signaling pathway, promoting NANOG expression, and inhibiting apoptosis.

This study investigated the use of 3D cell culture technology to explore hair follicle regeneration, examining the impact of the 3D cellular environment on hair follicle morphogenesis and the effects of microwell depth on spheroid formation.

This study developed a mathematical model to explore hair follicle regeneration mechanisms, showing that low spontaneous apoptosis rates help regenerate hair follicles after ionizing radiation, while high rates lead to degeneration during the catagen phase.

This review examines recent research on hair follicle stem cells, focusing on their maintenance, differentiation, and the potential for new follicle generation, but it reports no new experimental results.

This study found that the lncRNA lncRNA2919 is involved in hair follicle regeneration by downregulating growth-related genes, inhibiting cell proliferation, and promoting apoptosis in rabbit dermal papilla cells.

This study suggests that human induced pluripotent stem cells can be used to generate dermal papilla equivalent cells, potentially aiding hair follicle regeneration and drug discovery for hair diseases.

This study found that electric shaving was the most effective and safest method for preoperative hair removal in mice, compared to depilatory cream and sodium sulfide, which negatively affected wound healing.