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Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.

DHEA stimulates skin oil glands and could help postmenopausal women, with potential for acne and excessive hair growth treatments.

Activin helps skin growth and healing mainly through stromal cells and affects keratinocytes based on its amount.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Four genetic risk spots found for hair loss, with WNT signaling involved and a link to curly hair.

LGR5 helps maintain corneal cell characteristics and prevents unwanted changes by controlling specific cell signaling pathways.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Advanced human skin models improve drug development and could replace animal testing.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Dermal papilla cells help wounds heal better and can potentially grow new hair.

Women with PCOS often feel stigmatized and have mood issues, which can lower their sexual satisfaction, but proper treatment and support can help.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Isotretinoin's effects and side effects, like birth defects and depression, might be due to it causing cell death in various cells.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Low iron and vitamin D levels are linked to hair loss in women.

Some parents have a mild form of congenital adrenal hyperplasia without symptoms, and they usually don't need treatment.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

The cause of Frontal Fibrosing Alopecia is unclear, diagnosis involves clinical evaluation and various treatments exist, but their effectiveness is uncertain.

Light can turn on hair growth cells through a nerve path starting in the eyes.

The review recommends hormone replacement therapy for women with premature ovarian insufficiency to manage symptoms and protect health, with specific approaches for different groups.

The study showed that hair follicle stem cells can maintain and organize themselves in a lab setting, keeping their ability to renew and form hair and skin.

Metformin combined with lifestyle changes improves insulin resistance and reduces testosterone levels in women with PCOS more than lifestyle changes alone.

Nitric oxide gel helps heal skin burns faster by improving skin growth, hair regrowth, and blood vessel formation.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

Improving the environment and cell interactions is key for creating human hair in the lab.

MicroRNAs are crucial for controlling skin development and healing by regulating genes.