research Androgenetic Alopecia: Update on Etiology
AGA, a common hair loss, is caused by genetics, hormones, age, and environmental factors.
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research The Potential of Androgenic Alopecia Management from Plant Derivatives
Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.
research Hair Pathology
Triple horizontal scalp biopsies are 98% accurate in diagnosing hair loss, better than single biopsies.
research Efficacy of Oral Tofacitinib in the Treatment of Lichen Planopilaris
Oral tofacitinib significantly improves lichen planopilaris symptoms without adverse effects.
research Endocannabinoid-Like Molecule Oleoylethanolamide Promotes Sebaceous Lipid Synthesis
Oleoylethanolamide (OEA) safely boosts fat production in skin cells and may help treat dry skin and reduce inflammation.
research Androgenic Alopecia: Cross-Talk Between Cell Signal Transduction Pathways
Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
research Cosmetic Procedures in the Treatment of Alopecia
Some cosmetic procedures show promise for treating hair loss, but more research is needed to confirm their safety and effectiveness.
research Understanding Cancer Cells of Origin in Cutaneous Tumors
The document concludes that identifying the specific cells where skin cancers begin is important for creating better prevention, detection, and treatment methods.
research Positive Impact of Fish Oil on Diabetic and Hypercholesterolemic Skin Disorders
Fish oil improves skin health in people with diabetes and high cholesterol.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Aging and Anti-Aging in Hair and Hair Loss
Hair ages and thins due to factors like inflammation and stress, and treatments like antioxidants and hormones might improve hair health.
research Stem Cells and Their Niches
The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
research Percutaneous Drug Delivery to the Hair Follicle
Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
research Exosomes Derived From Umbilical Cord Mesenchymal Stem Cells Promote Hair Regrowth in C57BL/6 Mice Through Upregulation of the RAS/ERK Signaling Pathway
Exosomes from stem cells help hair regrowth by activating a specific signaling pathway.
research Glycogen Phosphorylase Inhibitor Promotes Hair Growth via Protecting from Oxidative Stress and Regulating Glycogen Breakdown in Human Hair Follicles
A new compound, HTPI, promotes hair growth by protecting cells from damage and regulating energy use.
research Adequate Nutrition and Premature Hair Graying: A Review of Literature
Good nutrition may help prevent premature hair graying.
research Jagged-1+ Skin Tregs Modulate the Innate Immune Response to Wound Healing
Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.
research Cell Death as an Architect of Adult Skin Stem Cell Niches
Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.
research Immune Niches for Hair Follicle Development and Homeostasis
Immune cells are crucial for hair growth and preventing hair loss.
research A Brief Study on Alopecia Areata
Alopecia areata causes hair loss with varied treatment responses and frequent relapses.
research Illuminating Microflora: Shedding Light on the Potential of Blue Light to Modulate the Cutaneous Microbiome
Blue light might help treat skin conditions by affecting the skin's bacteria.
research The Role of Wnt and Shh Signaling Systems in Noggin-Induced Tumorigenesis
Wnt and Shh signaling are key in noggin-induced tumors, and blocking them can slow tumor growth.
research Local Treatments for Alopecia Areata: An Update
Various local treatments for alopecia areata show promise, but individualized plans and more research are needed.
research Effect of Topical Gel Administration of Secretome Hypoxia Mesenchymal Stem Cells on IL-10 and TNF-α Gene Expression: An In Vivo Experimental Study in Male Wistar Rats with Fluconazole-Induced Alopecia
SH-MSCs gel can effectively treat alopecia by increasing IL-10 and decreasing TNF-α gene expression.
research AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis
AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
research Disrupted Cholesterol Biosynthesis and Hair Follicle Stem Cell Impairment in the Onset of Alopecia
Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
research Scarring Hair Follicle Destruction Is Driven by the Collapse of EGFR-Protected JAK-STAT1-Sensitive Stem Cell Immune Privilege
A protein called EGFR protects hair follicle stem cells, and when it's disrupted, hair follicles can be damaged, but blocking certain pathways can restore hair growth.
research An Update on Etiopathogenesis and Management of Alopecia
Personalized treatment plans combining natural and synthetic approaches are important for managing alopecia effectively.
research Expression of EZH2 in the Skin of Developing Human Fetuses and Adults: A Comparative Study
EZH2 levels decrease as fetuses develop and are higher in adult skin, which may affect skin growth and repair.
research MTOR Signaling in Hair Follicle and Hair Diseases: Recent Progress
The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.