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Young women in West Bengal, India, with PCOS often have estrogen resistance, leptin receptor issues, folate deficiency, T2DM, and acanthosis, commonly linked to obesity.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

IL-1 family cytokines are crucial for skin defense and healing, but their imbalance can cause skin diseases.

The document explains the genetic causes and characteristics of inherited hair disorders.

Keratosis pilaris is often linked to genetic mutations and causes skin and hair abnormalities, regardless of those mutations.

Restoring mitochondrial function in mice reversed their skin wrinkling and hair loss.

Notch signaling is essential for healthy skin and hair follicle maintenance.

A boy with severe immune deficiency and Epstein-Barr virus died from high-grade B-cell lymphoma.

Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.

Dermal EZH2 controls skin cell development and hair growth in mice.

FPHL is a common, age-related, genetic hair loss with unclear causes and limited treatment options.

The document concludes that various childhood hair and nail disorders exist, some may improve on their own, and advances in genetics and immunology could enhance treatment and counseling.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

The gene Ascl4 is not necessary for the development of hair, teeth, or mammary glands.

A rare benign skin tumor showed unusual features of sebaceous and sweat glands, important for correct diagnosis.

Screening for iron levels in patients with hair loss may help find a genetic iron overload condition early.

A Chinese male with a new genetic mutation has a skin condition and severe urinary issues, with treatments having mixed success.

Autoimmune diseases cause the immune system to attack the body, and management varies as some are curable and others are not.

Azathioprine can cause severe blood issues and hair loss, needing careful monitoring and possible discontinuation.

Mitochondrial reactive oxygen species are essential for skin and hair development.

Vitamin D and its receptor regulate skin functions like cell growth, immunity, hair cycle, and tumor prevention.

FOXN1 gene mutations cause a rare, severe immune disease treatable with cell or tissue transplants.

Hair loss in women, often not related to male hormones, increases with age and can cause significant emotional distress.

The study found that genetic differences related to hair growth and other traits help cashmere goats adapt to high-altitude environments.

A new genetic change in the DSC3 gene is linked to a rare condition causing hair loss and skin blisters in a child.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

The research showed that CRISPR/Cas9 can fix mutations causing a skin disease in stem cells, which then improved skin grafts in mice, but more work on safety and efficiency is needed.

Targeted therapy with Ustekinumab significantly improved a skin condition called ILVEN, which is caused by mutations in the CARD14 gene.

Specialized ribosomes affect aging in human skin cells.

Mouse touch-sensitive nerve cells adjust their connections based on competition with other similar cells.