![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
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research An Efficient Method for Isolation of Hair Papillae and Follicle Epithelium from Human Scalp Specimens
A new method helps isolate key hair components to study hair growth and loss.
research Changes in Murine Hair with Dietary Selenium Excess or Deficiency
Too much or too little selenium in the diet can cause hair loss and graying in mice.
research Topical Treatment with the Bacterium-Derived c-Met Agonist InlB321/15 Accelerates Healing in the Abrasion Wound Mouse Model
Applying InlB321/15 to wounds sped up healing in mice.
research Hair-Follicle Dermal Papilla and Sheath Fibroblasts Provide a Supportive Microenvironment for Human Skin Regeneration
Certain cells around hair follicles help improve skin regeneration for potential use in skin grafts.
research Chemotherapy-Induced Alopecia: A Novel Observation
Some patients' hair grew back black and white after chemotherapy.
research Drug Permeation Through Hair Follicles: Importance and Potential
Hair follicles are important for drug delivery through the skin, but better methods are needed to understand and improve this process.
research Mannan Oligosaccharides Improve the Fur Quality of Raccoon Dogs by Regulating the Gut Microbiota
Mannan oligosaccharides improve raccoon dogs' fur quality and overall health.
research Hirsutism Management Needs to Be More Patient Oriented
Hirsutism treatment should focus more on patient needs and quality of life.
research Hairy Math: Addition of Wnt-3a to Multiply Bulge Cells
Wnt-3a helps grow more skin stem cells, which could lead to new hair loss treatments.
research Abnormal Fingerprints and Immigration Delay Disease
Many adult women experience unexplained excessive hair shedding, often starting before age 40.
research In Other Journals: Summaries of Dermatological Studies from 2011
Cellulite may be linked to low adiponectin, isotretinoin with UVB can treat psoriasis effectively, permanent alopecia post-chemotherapy resembles a unique hair loss, deodorants may cause fragrance allergies, desmoplastic melanoma is becoming more common, and intensive UVB treatment can give long-term psoriasis remission.
research Keratins in Health and Cancer: More Than Mere Epithelial Cell Markers
Keratins help protect cells, aid in cancer diagnosis, and influence cancer behavior and treatment.
research Minoxidil: Mechanisms of Action on Hair Growth
Minoxidil boosts hair growth by opening potassium channels and increasing cell activity.
research Alopecia Areata Update
Half of people with Alopecia Areata may see hair regrowth within a year without treatment, but recovery is unpredictable.
research Balding Hair Follicle Dermal Papilla Cells Contain Higher Levels of Androgen Receptors Than Those From Non-Balding Scalp
Cells from balding scalps have more androgen receptors than cells from non-balding scalps.
research Bioengineering Skin Using Mechanisms of Regeneration and Repair
Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
research A Matter of Life and Death: Self-Renewal in Stem Cells
Stem cell self-renewal is complex and needs more research for full understanding.
research Evidence-Based Guideline for the Treatment of Androgenetic Alopecia in Women and Men – Short Version
Use minoxidil for hair loss treatment; assess results after 6 months.
research Androgen Actions on the Human Hair Follicle: Perspectives
Androgens have complex effects on hair growth, promoting it in some areas but causing hair loss in others, and our understanding of this is still evolving.
research Dermatology Position Paper on the Revision of the 1982 ACR Criteria for Systemic Lupus Erythematosus
The paper concludes that the 1982 criteria for diagnosing systemic lupus erythematosus need updating to improve accuracy and involve dermatologists in the process.
research Pharmacological Therapy of Benign Prostatic Hyperplasia/Lower Urinary Tract Symptoms: An Overview for the Practicing Clinician
Medications have become the main treatment for enlarged prostate symptoms, replacing surgery and watchful waiting.
research Human Hair Follicle: Reservoir Function and Selective Targeting
The human hair follicle can store topical compounds and be targeted for drug delivery with minimal side effects.
research Epidemiology of Vitiligo, Associated Autoimmune Diseases, and Audiological Abnormalities: Ankara Study of 80 Patients in Turkey
Vitiligo is linked to autoimmune diseases and hearing issues, so hearing tests are recommended for patients.
research Flares of Systemic Lupus Erythematosus During Pregnancy and the Puerperium: Prevention, Diagnosis, and Management
Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.
research Role of Genetics and Sex Steroid Hormones in Male Androgenetic Alopecia and Female Pattern Hair Loss: An Update
Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.
research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
research Regulated Proenkephalin Expression in Human Skin and Cultured Skin Cells
Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
research Gene-Wide Association Study Between the Aromatase Gene (CYP19A1) and Female Pattern Hair Loss
Aromatase gene variation may increase female hair loss risk.
research Diagnosis of Hyperandrogenism: Biochemical Criteria
The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.