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N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.

Spironolactone effectively reduces symptoms of hyperandrogenism but has some side effects.

Finasteride lowers scalp and blood DHT levels, potentially treating male-pattern baldness.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Epimorphin, a protein, plays a key role in the development of hair follicles in human fetuses, but it doesn't help in maintaining the stem cell population of the follicular skin layer.

Some congenital hair disorders improve with age and can be managed with treatments like minoxidil, retinoids, supplements, and gentle hair care, but there's no cure.

Scientists can grow human hair follicle stem cells in a lab without changing their nature, which could help treat hair loss.

A new model for hair regeneration in mice was created in 2015, which is faster and less invasive than the old method, producing normal hairs in about 21 days.

Cosmeceuticals may benefit skin health but need more research for efficacy and safety confirmation.

Targeting IL-17 could help treat pattern hair loss.

There is no significant link between alopecia areata and the PON1 enzyme polymorphisms studied.

Marie-Unna Hereditary Hypotrichosis is a rare genetic condition causing sparse hair growth, requiring specific recognition for proper care.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.

Older age, higher BMI, and family history of diabetes increase the risk of gestational diabetes in pregnant women.

Some hair loss disorders are caused by genetic mutations affecting hair growth.

Cells from the base of hair follicles help blood vessel cells survive and grow, which is important for healthy hair.

Human hair follicle stem cells show signs of low oxygen levels, which may be important for hair growth and preventing baldness.

Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.

Applying latanoprost on skin can stimulate hair growth with minimal side effects.

A 15-year-old with KID syndrome developed a rare skin condition called PEHFN.

Low-level laser treatment helps mice grow hair by increasing certain protein levels linked to hair growth.

Dengue virus can infect human hair follicle cells and may cause hair loss.

MC4R gene variants not linked to female hair loss.

The document suggests a rare skin condition might be caused by a genetic phenomenon.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.