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Using systemic drugs as creams for skin conditions shows promise, but more research is needed to confirm their effectiveness and safety.

Breast cancer skin metastases are rare, look different, and can be confused with other skin issues, so a biopsy is needed for accurate diagnosis.

Gene therapy shows promise for improving wound healing, but more research is needed for human use.

Researchers found a gene in hamsters that responds to male hormones and may be indirectly controlled by them.

The document is a detailed guide on skin conditions and treatments for dermatologists.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Vitiligo is a skin condition causing white spots, more common in women, often starts before age 20, and can affect mental health.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Toxic Shock Syndrome mainly affects menstruating women, can recur, and is linked to staph bacteria, with rapid treatment being crucial.

Some medicinal plants can help heal wounds and may lead to new treatments.

Myrtle has various health benefits and potential for medicine development.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Substances from Chinese medicines show promise for immune support and disease prevention, but the way they are processed affects their effectiveness.

The TGM3 gene's promoter region is key for skin and hair cell function and may aid gene therapy.

Recombinant cytokine therapy can cause skin reactions ranging from mild to severe.

Lichen planopilaris is a chronic, scarring hair loss condition with no definitive cure, requiring accurate diagnosis and treatment to manage symptoms.

Alpha-hydroxy acids, like glycolic acid, safely improve skin issues and work on all skin types.

The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Shen-Min, a hair growth supplement, likely caused acute hepatitis in a woman, improving after she stopped taking it.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.