research Drug Repurposing Patent Applications April–June 2021
Drug repurposing shows promise for treating many medical conditions.
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60-90 / 1000+ resultsresearch A Rapid, Simple, Liquid Chromatographic-Electrospray Ionization, Ion Trap Mass Spectrometry Method for the Determination of Finasteride in Human Plasma and Its Application to Pharmacokinetic Study
research Ocfentanil Testing in Hair from a Fatality Case: Comparative Analysis of a Lock of Hair Versus a Single Hair Fiber
Both a lock of hair and a single hair strand can show chronic drug use, but at least six single hairs are needed for accurate results.
research Contribution Of In-Utero Drug Exposure When Interpreting Hair Results In Young Children
Hair analysis alone can't confirm long-term drug exposure in children under 1 year old.
research Importance of Hair in Diagnosis, Management, and Monitoring of Dependent Subjects
Hair analysis is crucial for diagnosing, managing, and monitoring addiction.
research Association of Eight Single Nucleotide Polymorphisms of Chromosomes 20 and X with Androgenetic Alopecia Among Ethnic Han Chinese from Yunnan
Certain genetic markers on chromosome 20 are linked to hair loss in the Han Chinese from Yunnan.
research Alopecia and Associated Toxic Agents: A Systematic Review
Thallium, mercury, selenium, and colchicine strongly cause hair loss.
research Hair Analysis for Cannabinoids and Amphetamines in a Psychosis Incidence Study
Hair analysis for drugs in psychosis patients is unreliable due to varying hair growth rates.
research Emerging Unconventional Therapies for Alopecia Areata
New therapies for alopecia areata show potential but need more research.
research Experimental Investigations on Hair Fibers as Diffusion Bridges and Opiates as Solutes in Solution
Hair can absorb and transfer opiates when soaked in water, with damaged hair absorbing more.
research Analytical Method for the Biomonitoring of Bisphenols and Parabens by Liquid Chromatography Coupled to Tandem Mass Spectrometry in Human Hair
A new method accurately detects bisphenols and parabens in human hair.
research Men’s Health in the United States: A National Health Paradox
Men in the U.S. have more health issues, higher death rates from various diseases, lower life expectancy, and are less likely to seek healthcare.
research Optical Coherence Tomography: Promising In Vivo Measurement of Hair Shaft Cross Section
OCT is a reliable, noninvasive way to measure hair thickness.
research Disappearance of Tramadol and THC-COOH in Hair After Discontinuation of Abuse: Two Different Profiles
Tramadol and THC-COOH can be detected in hair for several months after stopping use.
research Candidate Gene Analysis of Alopecia Areata in Jordanian Population of Arab Descent: A Case-Control Study
The study found that a specific genetic variation in the TNFα gene is significantly linked to Alopecia Areata in the Jordanian Arab population.
research Genetic Control and Involvement in Hair Fiber Traits
research UPLC-MS/MS Method for the Simultaneous Quantification of Caffeine and Illicit Psychoactive Drugs in Hair Using a Single-Step High-Speed Grinding Extraction – Insights into a Cut-Off Value for Caffeine Abuse
The conclusion is that a new method can measure caffeine and drugs in hair, finding caffeine abusers have 70 times more caffeine than normal, with a proposed cut-off value for abuse.
research Adsorption of Diclofenac and PFBS on a Hair Keratin Dimer
Human hair keratin might be good for filtering out harmful substances from water.
research Doctor, You Must Examine My Creature Collection!: A Case Report of Delusional Infestation
A man wrongly believed he had parasites, showing that delusional infestation can affect men and is often linked with other psychiatric issues, but can be treated with antipsychotics.
research Herding Practices in the Keriya Valley (Xinjiang, China) During the Bronze and Iron Ages Using Stable Isotopic Analysis of Animal Hair
Ancient herders in the Keriya Valley fed their animals mainly C3 plants, with some C4 plant feeding possibly due to herd movement or seasonal changes.
research Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?
Finasteride, a hair loss drug, may cause sexual dysfunction and depression, but these effects are usually temporary and the drug is generally safe. More research is needed.
research Faculty Opinions Recommendation of Persistent Sexual Dysfunction and Depression in Finasteride Users for Male Pattern Hair Loss: A Serious Concern or Red Herring?
Finasteride, a hair loss treatment, may cause long-term sexual dysfunction and depression.
research Efficacy of Platelet-Rich Plasma Injection for the Treatment of Male Androgenetic Alopecia: A Systematic Review and Meta-Analysis of Changes in Hair Density
Platelet-rich plasma injections effectively increase hair density in men suffering from common hair loss.
research Minoxidil: An Alternative to Nephrectomy for Refractory Hypertension
Minoxidil effectively lowers blood pressure with few side effects.
research Rapid Determination of Finasteride in Human Plasma by UPLC-MS/MS and Its Application to Clinical Pharmacokinetic Study
New method measures finasteride in blood quickly and accurately.
research Floral Attractants in the Black Orchid Brasiliorchis Schunkeana: Clues for Presumed Sapromyophily and Potential Antimicrobial Activity
The black orchid Brasiliorchis schunkeana produces chemicals that attract certain insects and have potential antimicrobial properties.
research Distinct Phenotypic and Genomic Signatures Underlie Contrasting Pathogenic Potential of Staphylococcus Epidermidis Clonal Lineages
Staphylococcus epidermidis A/C strains are more antibiotic-resistant and infection-adapted, while B strains thrive in hair follicles.
research Phase I Safety and Pharmacokinetic Study of SU-014813 in Combination with Docetaxel in Patients with Advanced Solid Tumors
The drug combination was safe and showed promise in treating advanced tumors.
research Scaffolds for Epithelial and Hair Follicle Regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research Lupus Erythematosus Profundus With Multiple Overlying Cutaneous Ulcerations: A Rare Case
A patient with a rare form of lupus improved after treatment for skin ulcers and hair loss on the face and scalp.