58 citations,
October 2001 in “Dermatologic Clinics” Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.
43 citations,
December 2013 in “Seminars in Cell & Developmental Biology” Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.
42 citations,
July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
38 citations,
December 2012 in “Journal of Cutaneous Pathology” EVG staining is a valuable, simple, and cost-effective method for diagnosing various skin conditions in dermatopathology.
37 citations,
April 2012 in “British Journal of Dermatology” Female hair loss linked to metabolic syndrome, not in males.
36 citations,
August 2017 in “Journal of Cosmetic Dermatology” PRP with microneedling effectively treats hair loss, and dermoscopy helps evaluate results.
31 citations,
October 2002 in “Dermatologic Surgery” Minoxidil helps stabilize hair loss, increase density, and reduce shedding after hair transplant surgery.
30 citations,
June 2016 in “Journal of Human Genetics” Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.
30 citations,
January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
25 citations,
July 2019 in “Experimental Dermatology” Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
22 citations,
January 2014 in “International Journal of Trichology” Hair restoration surgery can lead to swelling, infections, scarring, numbness, hiccups, and poor hair growth.
20 citations,
June 2012 in “British Journal of Dermatology” Bleaching hair damages protein structure, especially keratin, leading to weakened hair.
17 citations,
December 2004 in “The Journal of Men's Health & Gender” Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
15 citations,
November 2010 in “International Journal of Dermatology” Women with AGA have higher lipid levels, increasing heart disease risk.
15 citations,
January 1988 in “Drugs” The document concludes that treatments for female hair loss and excessive hair growth are temporary and not well-studied.
14 citations,
April 2020 in “Journal of Cosmetic Dermatology” QR678 treatments were more effective and comfortable for male hair loss than PRP treatments.
13 citations,
September 2020 in “Dermatologic Therapy” Microneedling may help hair loss, but needs more research.
12 citations,
August 2019 in “BMC Medical Genetics” Certain MC4R gene variants are linked to higher BMI in obese women with PCOS but do not cause PCOS.
12 citations,
January 2017 in “Skin appendage disorders” Two patients with skin lupus were mistakenly thought to have a different scalp condition but improved with lupus treatment.
12 citations,
June 2016 in “Reviews in Endocrine and Metabolic Disorders” Some skin diseases and their treatments can negatively affect male fertility.
11 citations,
January 2015 in “Journal of The European Academy of Dermatology and Venereology” Hair loss gene linked to prostate issues.
11 citations,
June 2011 in “Expert Review of Dermatology” Skin reactions to drugs are common and can be deadly, usually requiring stopping the drug and may be better prevented with genetic testing in the future.
11 citations,
January 2011 in “Turkish Journal of Medical Sciences” Low iron levels are a significant risk factor for hair loss, while high vitamin D levels might be a response to hair loss, not a cause.
9 citations,
June 2019 in “Mycopathologia” Malassezia yeast linked to hair loss; ketoconazole helps treat it.
8 citations,
June 2020 in “International Journal of Dermatology” Men with early hair loss have lower vitamin D levels.
7 citations,
July 2018 in “Journal of Functional Biomaterials” A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.
7 citations,
January 1987 in “Archives of Dermatology” Most people using minoxidil for hair loss probably won't see significant improvement.
5 citations,
September 1998 in “Atlas of the oral and maxillofacial surgery clinics of North America” Hair transplantation and micrografting, used for baldness, involve moving hair follicles from hair-rich to bald areas, requiring careful procedure and post-care for success.
4 citations,
May 2005 in “Seminars in Plastic Surgery” Carlos Oscar Uebel developed a hair transplant method that looks natural, has low risk, and shows full growth in 6-12 months.
4 citations,
October 1988 in “Clinics in Dermatology” Dihydrotestosterone (DHT) is crucial for conditions like male-pattern baldness and acne, and measuring a byproduct, androstanediol glucuronide, is a better way to assess DHT's effects than DHT blood levels.