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    Glossary Hepcidin

    hormone regulating iron absorption and release in the body

    Hepcidin is a hormone produced by the liver that plays a crucial role in regulating iron levels in the body. It controls the absorption of iron from the diet and its release from storage sites, ensuring that iron levels remain balanced. Elevated hepcidin levels can lead to conditions like anemia, while low levels can cause iron overload disorders.

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    1. miR-761-hepcidin/Gpx4 pathway contribute to unexplained liver dysfunction in polycystic ovary syndrome by regulating liver iron overload and ferroptosis Gynecological Endocrinology · 2023 · 16 citations
    2. The Mask Mutation Identifies TMPRSS6 as an Essential Suppressor of Hepcidin Gene Expression, Required for Normal Uptake of Dietary Iron. Blood · 2007 · 9 citations
    3. Matriptase-2, A Novel Suppressor of Hepcidin. Blood · 2009
    4. Antihepcidin antibody treatment modulates iron metabolism and is effective in a mouse model of inflammation-induced anemia Blood · 2010 · 245 citations
    5. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone American Journal of Physiology-Endocrinology and Metabolism · 2014 · 53 citations
    6. The association between serum ferritin and 25-hydroxyvitamin D and metabolic syndrome in Korean women: the Korea National Health and Nutrition Examination Survey 2010–2012 Journal of Clinical Biochemistry and Nutrition · 2017 · 7 citations
    7. Gender difference in the relationship between the ferritin and homeostasis model assessment of insulin resistance in non-diabetic Korean adults PLOS ONE · 2018 · 4 citations
    8. Polycystic ovary syndrome and iron overload: biochemical link and underlying mechanisms with potential novel therapeutic avenues Bioscience Reports · 2022 · 2 citations
    9. Anabolic and Metabolic Effects of Testosterone and Other Androgens: Direct Effects and Role of Testosterone Metabolic Products Endocrinology · 2017 · 2 citations
    10. Iron Deficiency in Immune-Mediated Inflammatory Skin Diseases: A Missing Link Between Systemic Inflammation, Immunometabolism, and Disease Burden Cells · 2026
    11. Iron–Skin Axis: Exploring the Interplay between Iron Homeostasis and Skin Disorders Journal of Investigative Dermatology · 2025
    12. S3507 GI Bleed Leading to Discovery of Hereditary Hemochromatosis The American Journal of Gastroenterology · 2020
    13. Carence en fer et troubles digestifs Transfusion Clinique et Biologique · 2014
    14. Regulation of Epidermal Ferritin Expression Influences Systemic Iron Homeostasis Journal of Investigative Dermatology · 2023 · 6 citations
    15. Anemia na COVID longa: características e correlações clínicas Revista Eletrônica Acervo Saúde · 2026
    16. Promising applications of red cell distribution width in diagnosis and prognosis of diseases with or without disordered iron metabolism Cell Biology International · 2023 · 17 citations
    17. Novel Mutation in the Hemojuvelin Gene (HJV) in a Patient with Juvenile Hemochromatosis Presenting with Insulin-dependent Diabetes Mellitus, Secondary Hypothyroidism and Hypogonadism American Journal of Case Reports · 2020 · 3 citations
    18. Untangling the hairy issue of iron deficiency: Making progress Journal of The American Academy of Dermatology · 2011 · 1 citations
    19. Genetic, hormonal and metabolic aspects of PCOS: an update Reproductive Biology and Endocrinology · 2016 · 258 citations
    20. Protoporphyrin IX: the Good, the Bad, and the Ugly Journal of Pharmacology and Experimental Therapeutics · 2015 · 138 citations
    21. Dermal White Adipose Tissue: A Newly Recognized Layer of Skin Innate Defense Journal of Investigative Dermatology · 2019 · 49 citations
    22. Iron deficiency and diffuse nonscarring scalp alopecia in women: More pieces to the puzzle Journal of The American Academy of Dermatology · 2010 · 30 citations
    23. Telogen effluvium in daily practice: Patient characteristics, laboratory parameters, and treatment modalities of 3028 patients with telogen effluvium Journal of Cosmetic Dermatology · 2021 · 10 citations
    24. Gender difference in relationship between serum ferritin and 25-hydroxyvitamin D in Korean adults PLOS ONE · 2017 · 10 citations
    25. Obstructive sleep apnea, low transferrin saturation levels, and male‐pattern baldness International Journal of Dermatology · 2018 · 5 citations
    26. Ovarian Leydig cell tumor and postmenopausal hirsutism with signs of virilisation Case Reports · 2021 · 4 citations
    27. Hormones Elsevier eBooks · 2018 · 4 citations
    28. Case 33-2015 The New England Journal of Medicine · 2015 · 2 citations
    29. Diuretics Side effects of drugs annual · 2018 · 1 citations
    30. Assessment of the tolerability and efficacy of supplementation containing micronized and emulsified ferric pyrophosphate in patients with iron deficiency — an observational study Ginekologia Polska · 2026