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Prednisone reduces organ mast cell infiltration but does not alter the abnormal appearance of mast cells in systemic mastocytosis.

Metreleptin treatment significantly improved metabolic health in a boy with congenital generalized lipodystrophy.

Two siblings had a rare immune disorder caused by a FOXN1 gene mutation.

A newborn with congenital syphilis had unusual hair loss possibly caused by the infection.

Travel history and tick-borne diseases should be considered in unexplained fevers for timely diagnosis and treatment.

Autoimmune hepatitis in children often affects girls and can be treated successfully with medication.

Severe digestive issues in DRESS need early endoscopy for better treatment.

A patient with Sézary syndrome showed improvement after treatment and the study suggested follicular mucinosis might indicate future lymphoma risk.

Alopecia mucinosa on the face can be linked to mycosis fungoides, a type of lymphoma.

A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.

People with Mucopolysaccharidoses often have skin problems like thick skin and extra hair, and recognizing these can help diagnose and treat the condition early.

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

Albendazole may cause hair loss.

Newborn screening and gene therapy are expected to improve outcomes for Omenn syndrome patients.

A three-year-old girl survived a rare serious infection caused by BCG vaccination, which improved after treatment with a leprosy drug.

The document concludes that skin and nail changes can indicate various underlying health conditions.

Even a small melanoma can be deadly if not removed, regardless of the patient's age.

Using old drugs for new uses can help treat rare immune deficiencies.

Childhood cancer diagnosis leads to long-term physical and emotional health issues in parents.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Skin problems are very common in people with systemic lupus erythematosus and important for diagnosis.

Flutamide rarely causes liver toxicity in prostate cancer patients.

Children, especially teenagers, can get severe SARS-CoV infection with symptoms similar to adults, but they typically recover well with supportive care.

Zinc is crucial for nutrition, especially in patients with specific health conditions, and requires careful supplementation and monitoring.

Oral retinoids are effective for severe skin conditions but require careful use due to side effects.

Recognizing oral symptoms can help diagnose and treat blood and nutritional diseases early.

Understanding the genetics of rare inherited ichthyosis syndromes is key for better treatments and genetic counseling.

Children generally have milder SARS symptoms than adults, with good outcomes and no deaths reported, but long-term effects are unclear.

Some people experience severe, long-lasting side effects from fluoroquinolone antibiotics, leading to the recommendation of limited use and increased awareness of these risks.