research Wnt/β-Catenin Signaling: Function, Biological Mechanisms, and Therapeutic Opportunities
The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.
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660-690 / 1000+ results research An Autopsy Case of Unicentric Castleman's Disease Associated with Bronchiolitis Obliterans
A woman with Castleman's disease died from respiratory failure due to bronchiolitis obliterans.
research Clinical Alert
In 2002, various drugs caused serious side effects, including vitamin B12 deficiency, heart issues, blindness, hypersexuality, allergic reactions, blood clotting problems, pupil dilation, capillary leak syndrome, muscle breakdown, hepatitis, skin reactions, and lupus.
research Dystrophic Anagen Effluvium Occurring During Pegylated Interferon-α-2a/Ribavirin Therapy
A woman's hair loss during Hepatitis C treatment with PEG-INF-a-2a and Ribavirin was reversible after stopping the medication.
research Clinico-Epidemiological Aspects of Cutaneous Lesions in Injecting Drug Users Visiting an Oral Substitution Therapy Centre: A Cross-Sectional Study
Most injecting drug users in the study had hepatitis C and skin problems, which moderately affected their quality of life.
research C002 Vasculitis: A Differential Diagnostic Approach
The document concludes that corticosteroids effectively treat vasculitis allergica in over 90% of cases, with long-term kidney issues being the main adverse outcome.
research Oral Tofacitinib: A Promising Treatment in Atopic Dermatitis, Alopecia Areata, and Vitiligo
Oral tofacitinib shows promise in treating atopic dermatitis and alopecia areata, but only slight improvement in vitiligo.
research A Clinicopathologic Study of Lichen Planopilaris Among Men
Most men with lichen planopilaris had it confirmed by biopsy and often had thyroid issues, sexual dysfunction, or prostate cancer, hinting at a link with hormonal problems.
research Ingestion of Minoxidil Associated with Elevated Transaminases in the Absence of Ischemic Hepatitis
Minoxidil ingestion can raise liver enzyme levels.
research Misdiagnosis as Asphyxiating Thoracic Dystrophy and CMV-Associated Hemophagocytic Lymphohistiocytosis in Shwachman-Diamond Syndrome
Patients with Shwachman-Diamond syndrome often get misdiagnosed due to a wide range of symptoms, including immune system problems and bone abnormalities.
research Phytochemical and Pharmacological Investigations of Aftimoon (Cuscuta Reflexa)
Aftimoon (Cuscuta reflexa) has various health benefits, including anti-inflammatory and anticonvulsant effects.
research Ketoconazole Therapy for Women with Acne and/or Hirsutism
Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.
research Traditional Uses, Phytochemistry, Pharmacology, Toxicity and Clinical Application of Traditional Chinese Medicine Cynoglossum Amabile: A Review
Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.
research Clinical Application of Renshen Yangrong Tang
Renshen Yangrong Tang is effective for treating various disorders linked to qi and blood deficiency.
research Misoprostol Therapeutics Revisited
Misoprostol has many medical benefits, including protecting against injuries, aiding in disease treatment, and improving drug effects.
research Minerva
Minoxidil is better for female hair loss without hormonal issues, cyproterone acetate for those with; people with treated congenital heart disease have lower life quality; personality differs in types of infertility; oral terbinafine is best for toenail fungus; bladder training reduces incontinence; nurse clinics help with heart disease; weight loss improves body composition and liver disease; computer training cuts drug errors.
research Adverse Drug Reactions and Interactions: Case Studies
Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.
research Clinical Case of Manifestation of Toxic Keratitis with Vitamin A Intoxication
Excessive vitamin A intake can cause eye damage, but recovery is possible with proper treatment.
research Reporting on Adverse Clinical Events
Some medications and supplements can cause serious side effects, including hair loss, heart rhythm problems, liver injury, and other health issues.
research The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases
Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.
research Lack of Classic Histology Should Not Prevent Diagnosis of Necrolytic Acral Erythema
Consider necrolytic acral erythema in similar cases and treat with oral zinc sulfate.
research Cutaneous Necrosis After Injection of Polyethylene Glycol–Modified Interferon Alfa
Some patients receiving pegylated interferon alfa injections developed skin necrosis, requiring treatment adjustments or discontinuation.
research 66-Year-Old Woman With Painless Vesicular Lesions
A 66-year-old woman with skin lesions and other symptoms improved after treatment for porphyria cutanea tarda.
research Use of Androgen Lowering Medications Finasteride and Dutasteride Do Not Substantially Alter Risk of Incident HCV-Related Hepatocellular Carcinoma in Men
Androgen lowering medications don't significantly change HCV-related liver cancer risk in men.
research 66-Year-Old Woman With Painless Vesicular Lesions
A woman was diagnosed with porphyria cutanea tarda and improved with phlebotomy and lifestyle changes.
research Lichenoid Dermatitis from Interferon Alpha-2a in a Patient with Metastatic Renal Cell Carcinoma and Seronegative HCV
A patient with advanced kidney cancer and no hepatitis C developed skin inflammation due to a drug called interferon alpha-2a.
research Seborrheic Dermatitis: Three Novel Trichoscopic Signs and Its Correlation to Malassezia sp. Colonization
Researchers found a new sign of fungal infection in some patients with Seborrheic Dermatitis.
research Evidence-Based and Potential Benefits of Metformin in Polycystic Ovary Syndrome: A Comprehensive Review
Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
research Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease Are Characterised by Interferon-γ-Expressing Th1 Cells and IL-17A/IL-22-Expressing Th17 Cells and Respond to Anti-IL-12/IL-23 Antibody Treatment
Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.
research Baiting Proteins with C60
C60 fullerenes can alter protein function and may help develop new disease inhibitors.