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Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Tofacitinib is safe and effective for severe alopecia areata, but hair loss may return 2 months after stopping treatment.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The guidelines suggest a detailed approach to diagnosing and treating lupus, with a focus on regular check-ups, personalized medicine, and a range of drug options for different cases.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Visible light can damage skin and most sunscreens don't block it well; more research is needed on its effects and protection methods.

Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

A man with severe hair loss and skin disease regrew his hair with no side effects after taking tofacitinib.

Hair follicle dermal stem cells are key for regenerating parts of the hair follicle and determining hair type.

Opioid painkillers can cause many side effects, including breathing problems and addiction, but are generally considered safe when used properly.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

Wnt signaling controls whether hair follicle stem cells stay inactive or regenerate hair.

Oestrogens are key for bone growth during puberty in both boys and girls.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.

Omeprazole effectively treats severe acid reflux in children for short-term use, but long-term safety needs more research.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Effective treatments for male pattern baldness include oral finasteride and topical minoxidil, while topical minoxidil is best for female pattern baldness.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Palliative chemotherapy is cost-effective for advanced gastric and colorectal cancer but not clearly for pancreatic-biliary cancer.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.