research Metabolic Dysfunction in Female Mice with Disruption of 5α-Reductase 1
Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
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research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Prospective Metabolic Evaluation of 150 Consecutive Patients Who Underwent Gastric Exclusion
Gastric exclusion surgery caused major weight loss and health improvements but led to some anemia and vitamin deficiencies.
research Rodent Models in Placental Research: Implications for Fetal Origins of Adult Disease
Using rodents for research shows that health problems in the womb can cause diseases later in life.
research Gastrointestinal Physiology in Obesity
Obesity is linked to many gastrointestinal diseases and needs more research for treatment development.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It's Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Insulin Resistance as a Risk Factor for the Development of Type 2 Diabetes Mellitus: A Systematic Approach
Insulin resistance increases the risk of developing type 2 diabetes and other health issues.
research Calcineurin-Based Immunosuppression in Renal Transplantation: Focus on Efficacy, the Role of Steroids, and Cardiovascular Risk
Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.
research Finasteride Delays Atherosclerosis Progression and Reduces Hepatic Inflammation in Low-Density Lipoprotein Receptor-Deficient Mice
Finasteride may slow down heart disease by lowering cholesterol and reducing inflammation.
research Global Adiposity and Thickness of Intraperitoneal and Mesenteric Adipose Tissue Depots Are Increased in Women With Polycystic Ovary Syndrome
Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
research Prevalence of Hepatic Steatosis in Women with Polycystic Ovary Syndrome
Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
research Hepatic Adenoma in an Adolescent With Elevated Androgen Levels
A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycemia, Elevated Hepatic Glycogen Storage, and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Triglycerides, Independent of Ferriman Gallwey Score, Is a Main Determinant of Free Testosterone Index in PCOS
High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
research Identification of Hepatic Molecular Mechanisms of Action of Alpha-Tocopherol Using Global Gene Expression Profile Analysis in Rats
Vitamin E affects liver metabolism, enhancing stress resistance, reducing blood clotting, and altering hormone processing.
research Neural, Adipocyte and Hepatic Differentiation Potential of Primary and Secondary Hair Folicle Stem Cells Isolated from Arbas Cashmere Goats
Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.
research Evaluation of Clinical Adverse Effects and Laboratory Changes in Patients with Acne Vulgaris Treated with Oral Isotretinoin
Isotretinoin is safe and effective for acne, with common side effects like dry lips; serious side effects are rare.
research Increased Androgen Bioavailability Is Associated With Non-Alcoholic Fatty Liver Disease In Women With Polycystic Ovary Syndrome
Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
research Nonalcoholic Fatty Liver Disease and Polycystic Ovary Syndrome
People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
research Adverse Reactions to Oral Retinoids: An Update
Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.
research Lipin 1 Gene Polymorphisms in Polycystic Ovary Syndrome
Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
research Bioequivalence Study of Finasteride
Finasteride's two formulations absorb similarly, showing bioequivalence.
research Comparison of Metformin and N-Acetylcysteine on Metabolic Parameters in Women with Polycystic Ovarian Syndrome
N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.
research Isotretinoin Treatment of Acne and Related Disorders: An Update
Isotretinoin effectively treats severe acne and similar conditions, but has common, mostly reversible side effects, requiring careful patient monitoring.
research Role of Plasminogen Activator Inhibitor Type 1 (PAI-1) in PCOS Patients
People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
research Evaluation of Metabolic and Hormonal Parameters in Women with PCOS Living in the Black Sea Region
Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.
research Study on Toxicity of Hydrocortisone 17-Butyrate 21-Propionate: Subacute Toxicity in Dogs by Percutaneous Administration
Hydrocortisone 17-butyrate 21-propionate ointment caused reversible side effects like skin issues, weight gain, and organ changes in dogs.
research The Rotterdam Study: 2010 Objectives and Design Update
The Rotterdam Study aims to understand various diseases in older adults.
research Multidisciplinary Treatment of Obesity with a Protein-Sparing Modified Fast: Results in 668 Outpatients
A weight loss program with a special fast helped patients lose an average of 41-47 pounds and improved their health, but maintaining the weight loss was challenging.
research Gerbils
Proper care and diet are crucial to prevent health issues in gerbils.