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Medications for glucose metabolism and weight control, combined therapy options, and herbal medicines may help regulate menstrual cycle in adolescents with PCOS.

Gender-affirming hormone therapy affects metabolism differently based on treatment type.

Eating less can improve stem cell function and increase lifespan.

Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

Liver transplantation is a viable option for children with propionic acidemia, improving quality of life and diet, but does not remove all risks and long-term brain outcomes are uncertain.

Inhibitors of 11β-HSD1 show potential for treating type 2 diabetes but require more testing for safety and effectiveness.

Spinach-derived thylakoid supplements plus a low-calorie diet helped obese women with polycystic ovary syndrome lose weight and improve their metabolism.

Changes in gut bacteria can contribute to the development of Polycystic Ovary Syndrome (PCOS), affecting metabolism, immunity, and causing inflammation. Treatments may involve adjusting these factors.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

The Rotterdam Study aims to understand various diseases in older adults.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Enzyme replacement therapy improved multiple symptoms of homocystinuria in mice.

New guidelines stress early diagnosis and lifestyle changes to manage metabolic syndrome and prevent complications.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Simvastatin may help manage symptoms in women with non-classic congenital adrenal hyperplasia by lowering cholesterol and certain hormone levels.

Finasteride and methadone don't increase advanced liver disease risk in HCV+ male veterans.

Vitamin D is crucial for skin health and managing skin diseases.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Myo-inositol supplements may improve insulin sensitivity and help with conditions like PCOS and gestational diabetes, but more research is needed.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Early detection and stopping the drug are key to managing DRESS, and careful monitoring is important due to possible severe reactions.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Male rats have androgen receptors in their liver, which are different from proteins that bind estrogen.

Taking L-tryptophan supplements might cause a condition similar to scleroderma in some people, which can get better after stopping the supplement and starting corticosteroid therapy.

Some skin problems can be signs of diabetes or other metabolic diseases and recognizing them can help diagnose and treat these diseases early.