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This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.

This study presented two cases of chronic hypervitaminosis A in adults, highlighting the first reported instance of hepatic cirrhosis due to long-term beef liver consumption.

This review outlines the major health consequences of anabolic-androgenic steroid abuse, with a focus on sexual and reproductive issues, and suggests management prioritizes cessation and relapse prevention due to lack of robust randomized trials.

This review discusses female hyperandrogenism, detailing diagnostic criteria and treatment options without reporting new study results; it emphasizes improving health and quality of life for affected women.

This study reviewed isotretinoin's effectiveness in treating moderate to severe acne and discussed the need to balance its robust treatment benefits with careful monitoring due to significant physiological and psychological side effects.

This review discusses the potential benefits of myo-inositol supplementation for insulin resistance-related disorders and diabetic complications, but reports no new clinical results.

This review discusses the range and causes of adipose tissue diseases, emphasizing genetic and acquired forms of lipodystrophy, but it reports no new clinical results.

This review covers the diagnosis of polycystic ovary syndrome and the management of related infertility, describing evaluation and initial treatment steps, without presenting new clinical results.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

This study found that in PCOS patients, variations in the lipin 1 gene, particularly the intron 1 SNP, may protect against insulin resistance and glucose intolerance, highlighting a potential genetic factor in the disorder's cardiometabolic complications.

5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

This review highlights that bicalutamide, a non-steroidal antiandrogen used in prostate cancer treatment, is mainly effective through its (R)-enantiomer and emphasizes the need to monitor its adverse effects despite its targeted antiandrogenic action.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

This study demonstrated that elevated glucocorticoid levels in transgenic mice led to pancreatic exocrine cells transforming into hepatocyte-like cells, resulting in pancreatic dysfunction.

This case study describes hair loss as a potential late complication of multisystem inflammatory syndrome in children, observed in a 7-year-old girl who developed Telogen effluvium 73 days post-diagnosis.

This study found that cyclosporine-A might significantly increase the risk of cerebral venous and arterial thrombosis in patients with aplastic anemia.

In this study, FOL-026, a peptide based on osteopontin, was shown to promote angiogenesis and stimulate vascular cell proliferation and migration through neuropilin-1, similar to VEGF, suggesting potential therapeutic applications in vascular repair and angiogenesis-related conditions.

This review highlights how diabetes affects stem and progenitor cells through altered signaling and homeostasis, impacting tissue function and complicating diabetic therapy efforts; new clinical results are not presented.

In this review, researchers summarized findings from clinical studies on mesenchymal stem cells for diabetes treatment, noting their potential but also highlighting challenges like small sample sizes and the need for standardization in preparation and delivery methods.

This study found that hair follicle mesenchymal stem cells improved liver function and pathology in a mouse model of liver cirrhosis, potentially by inhibiting the TGF-β/Smad pathway and reducing hepatic stellate cell activation.

This study observed that radiation exposure in male rats activated hepatic stellate cells and the PI3K/Akt signaling pathway, mediated by TGF-β1, contributing to liver injury, while the use of a signaling pathway inhibitor reduced these effects.

The study observed that Hispanic women with PCOS had significantly higher odds of having NASH compared to non-Hispanic women, suggesting routine screening may be beneficial in this high-risk group.

This review discusses the roles of resident macrophages in the liver and lung, emphasizing their unique contributions to maintaining tissue homeostasis and the interface between circulation and external environments, but reports no new findings.

This joint consensus statement from several Polish professional associations discusses strategies for improving obesity treatment and enhancing primary care's role in managing obesity, with no new empirical data reported.

This article reviews the complications and health risks associated with polycystic ovary syndrome and reports no new clinical findings.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Diabetes often causes various skin problems and complications.

This pilot study found that hair metabolome analysis may help differentiate pregnancy complications from healthy pregnancies by revealing significant metabolite differences between trimesters.

In this study, researchers found significant neuropsychiatric complications from dengue infection, such as anxiety, depression, and even mania, during acute and recovery phases, linked to inflammatory responses and potential direct viral effects on the central nervous system.

This study describes how robotic surgery has been widely adopted across various specialties in Hungary, showing benefits like lower complication rates and quicker recovery times, but also acknowledges challenges such as high costs and extended learning periods.