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Orphan drug benefit scores in Germany are influenced by phase III data and lack of alternatives, but not linked to price or discounts.

A gene variant causes patched hair loss in mice, similar to alopecia areata in humans.

The document concludes that patient outcomes for Congenital Adrenal Hyperplasia are often not ideal because of poor management and a need for better diagnosis and treatment methods.

Skin changes can indicate starvation and nutritional deficiencies in anorexia nervosa.

Dosage regime inventions can be patentable in China, but legal uncertainty exists.

Mast cells play a significant role in hair loss conditions like male pattern hair loss and alopecia areata.

Forsythiasides have multiple health benefits but may cause pseudoallergic reactions, and more research is needed.

The research identified key molecules that help hair matrix and dermal papilla cells communicate and influence hair growth in cashmere goats.

Scientists have found a way to create hair follicles from human stem cells, which could potentially be used to treat hair loss.

Hair care products can cause skin irritation and allergies.

A new filler made from patients' own skin and hair significantly improved depressed scars with no severe complications.

Dense-packing follicular unit extraction is a safe and effective way to treat extensive scarring alopecia.

5% topical minoxidil improves hair density and quality in monilethrix patients.

Fasting in hens affects thyroid hormones, which regulate feather and hair growth.

CRABP2 helps increase the growth of cells important for hair growth by activating a specific growth pathway.

A variant in the ADAM17 gene causes hair loss by increasing protein degradation through TRIM47.

Hair restoration follows a specific pattern.

A new mutation in the Hairless gene causes hair loss in two Pakistani families.

The document concludes that advanced methods show the presence of P. acnes in acne lesions but do not prove it causes acne.

Mice with damaged skin or hair follicles are more susceptible to anthrax infection.

Pemetrexed is as effective as docetaxel but has fewer side effects for treating nonsmall-cell lung cancer after EGFR-TKI therapy failure.

Ten miRNAs may play key roles in starting secondary hair follicle development in sheep foetuses.

LSD1 and HSP90 help heal skin wounds by changing hair follicle stem cells' metabolism.

PRP with finasteride is better for hair regrowth than minoxidil with finasteride.

New gene discoveries have improved diagnosis and treatment for skin and hair disorders, but more research is needed to fully understand them.

Most patients with autoimmune blistering diseases experienced some hair loss, which may be underreported and linked to disease severity.

Early diagnosis and personalized treatment are crucial for managing hair loss in children.

Acne is linked to complex skin microbe interactions, and new findings suggest microbiome-based treatments could be effective.

Hair growth and development are controlled by specific signaling pathways.