3 citations
,
May 2004 in “Journal of neurosurgery” This study found that endoscopy-assisted craniectomies with postoperative molding helmets led to excellent outcomes in infants with sagittal synostosis, with low morbidity and minimal complications.
1 citations
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June 2023 in “Journal of Visualized Experiments” This study describes a new intravital microscopy method for observing intestinal regeneration by tracking crypt dynamics in living mice after laser-induced tissue damage, revealing events like crypt fission, fusion, and disappearance over multiple weeks.
August 2026 in “Journal of Biomedical Materials Research Part B Applied Biomaterials” This study found that natural tea trichomes accelerated wound healing and provided photoprotection in a mouse model, suggesting potential as a sustainable biomaterial for skin repair due to its antioxidant properties and ability to enhance tissue regeneration and reduce UV-induced skin damage.
April 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that human skin melanocytes with low mutation burdens are smaller, less dendritic, and exhibit stem-like features, often residing in UV-protected hair follicles, suggesting their role in replenishing sun-damaged epidermis.
October 2025 in “Brazilian Journal of Hair Health” This narrative review identifies telogen effluvium as a growing concern linked to weight-loss interventions, such as GLP-1 receptor agonists and bariatric surgery, attributing hair loss to systemic and metabolic stress rather than permanent hair follicle damage.
January 2025 in “eScholarship@McGill (McGill)” In this study, loss of the Notch ligand Jag2 in mouse epidermal cells disrupted early differentiation and affected the structure and behavior of adjacent melanocytes, highlighting Jag2's role in epidermal differentiation and tissue homeostasis.
August 2021 in “Oxford University Press eBooks” This chapter discusses various skin functions and structures involved in protection, immune response, and homeostasis, but it reports no new research findings.
August 2015 in “Free Radical Biology and Medicine” This study explores the correlation between sirtuins' expression, histone deacetylation, and redox status in young and old monozygotic twins to understand their role in age-related mechanisms.
September 2022 in “Journal of Theoretical Biology” This study developed a mathematical model to explore hair follicle regeneration mechanisms, showing that low spontaneous apoptosis rates help regenerate hair follicles after ionizing radiation, while high rates lead to degeneration during the catagen phase.
1 citations
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April 2022 in “Journal of Biological Regulators and Homeostatic Agents/Journal of Biological Regulators & Homeostatic Agents” This study reported that among 1337 patients receiving biocompatible artificial hair implants, common side effects included mild inflammation (7%) and itching (<3%), while patient satisfaction was high at 96%, though COVID-19 may have impacted some results.
2 citations
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October 2020 in “Annals of Oncology” This analysis discusses the role of genetic factors, particularly male hormones and specific gene variants, in influencing sex differences and potential susceptibility to severe COVID-19 outcomes, but notes that conclusive evidence is lacking, highlighting the need for larger studies.
July 2005 in “Journal of The American Academy of Dermatology” This article discusses the various uses of the cotton-tipped applicator in dermatologic surgery, highlighting its innovative role as a suture scissors stabilizer, but reports no clinical results.
85 citations
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December 2017 in “Developmental Biology” This review discusses mammalian models of epimorphic regeneration to define a vertebrate regeneration blastema, concluding that regenerative failure likely stems from cellular responses to the microenvironment after injury, not progenitor cell availability, and calls for targeted modification studies in mammals to advance human regeneration.
48 citations
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May 2023 in “Nature Communications” In a study on muscle regeneration in mice, researchers found that platelet-secreted CXCL7 is crucial for recruiting neutrophils to injury sites, aiding early muscle repair and optimal regrowth, suggesting potential therapeutic uses for boosting muscle healing.
6 citations
,
October 2016 This article reviews the complex structure and molecular composition of hair keratins, highlighting their self-assembly process and implications for keratin extraction techniques, but reports no new experimental results.
January 2019 in “Springer eBooks” Platelet-rich plasma therapy may have benefits and is generally safe, but more research is needed to confirm its effectiveness and safety.
This study found that elastin-like recombinamer (ELR) wound dressings promote tissue regeneration and stability without rejection in ex vivo and in vivo models, indicating potential for hard-to-heal wound treatment.
1160 citations
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November 2018 in “Physiological Reviews” This review discusses the potential of single cell technologies to improve understanding and treatment of impaired wound healing and reports no new clinical results.
293 citations
,
November 2011 in “Nature” This study found that the circadian clock regulates the activation state of murine epidermal stem cells, affecting tissue homeostasis and susceptibility to tumorigenesis when disrupted.
260 citations
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December 2012 in “Cold Spring Harbor Perspectives in Biology” This review discusses the significant role of Wnt signaling in skin development, homeostasis, and disease, highlighting recent advances in understanding its diverse functions, but reports no new experimental results.
256 citations
,
October 2013 in “Nature Communications” This study demonstrates that bioengineered lacrimal gland germs can successfully develop and restore tear production and ocular surface protection in a mouse model with lacrimal gland dysfunction.
179 citations
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October 2018 in “American Journal of Clinical Dermatology” This review outlines various dermatologic adverse events associated with targeted therapies and immunotherapies, emphasizing the need for collaboration between dermatologists and oncologists to manage these effects effectively; it reports no new clinical findings.
120 citations
,
February 2009 in “Apoptosis” This review examines apoptotic and anti-apoptotic mechanisms in skin homeostasis and related diseases but presents no new research findings.
119 citations
,
November 2014 in “Trends in Cell Biology” This review discusses the mechanisms and pathways of FGFR signalling and its roles in development, disorders, and therapeutic targeting, but reports no new clinical results.
119 citations
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January 2012 in “Nutrition & Metabolism” This article suggests that modern lifestyle changes, including diet, stress, and chronic anti-inflammatory medication use, may disrupt the natural process of inflammation resolution, increasing vulnerability to chronic disease.
119 citations
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June 2005 in “Journal of Molecular and Cellular Cardiology” This article reviews the therapeutic potential of potassium channel openers for various conditions related to metabolic distress but does not report new clinical results; it emphasizes the need for further research.
105 citations
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September 1995 in “Journal of The American Academy of Dermatology” This review discusses the use of recombinant cytokines as therapeutic agents in clinical settings and describes the range of cutaneous complications associated with their use, including both minor and severe skin reactions.
65 citations
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June 2020 in “Stem Cell Research & Therapy” This review discusses recent advances in how proinflammatory cytokines affect epidermal stem cell function during skin wound healing and introduces potential therapies targeting these cells and cytokines.
65 citations
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February 2017 in “Pflügers Archiv - European Journal of Physiology” This review examines the roles of macrophages and Langerhans cells in skin homeostasis and suggests that understanding these functions can aid in developing therapies for skin and hair regeneration, but it reports no new research findings.
57 citations
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January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.