18 citations,
October 2021 in “Frontiers in Physiology” Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
4 citations,
March 2022 in “Pharmaceutics” Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
1 citations,
March 2023 in “Aggregate” A new hydrogel with micronized amnion helps achieve better, scar-free skin healing.
August 2023 in “Military Medical Research” Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.
August 2023 in “International Journal of Molecular Sciences” Human skin xenografting could improve our understanding of skin development, renewal, and healing.
3 citations,
December 2022 in “npj Regenerative Medicine” HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.
2 citations,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
August 2024 in “Stem Cell Research & Therapy” New regenerative therapies show promise for treating hair loss.
March 2024 in “Cosmetics” New regenerative techniques show promise for improving skin, healing wounds, and growing hair.
5 citations,
December 2021 in “Frontiers in Cell and Developmental Biology” Enzymes called PADIs play a key role in hair growth and loss.
February 2024 in “Plastic and Reconstructive Surgery – Global Open” Stem cell therapies show promise for hair regrowth in androgenetic alopecia.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
163 citations,
March 2012 in “BMC biology” Stem cell niches support, regulate, and coordinate stem cell functions.
68 citations,
November 2011 in “The American journal of pathology” Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.
159 citations,
October 2015 in “Science Advances” Blocking JAK-STAT signaling can lead to hair growth.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Most patients experienced mild to moderate skin problems during a trial for a desmoid tumor treatment.
212 citations,
May 2012 in “Genes & Development” Planarian regeneration begins with a specific gene activation caused by injury, essential for healing and tissue regrowth.
77 citations,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
33 citations,
September 2019 in “Dermatologic Surgery” Using a special stem cell formula on the scalp once a month for six months helped people with hair loss grow more hair.
1 citations,
September 2023 in “eLife” TLR2 is important for hair growth and can be targeted to treat hair loss.
September 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Freezing gamma-irradiated amniotic fluid may help hair growth and speed up the growth phase.
1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
178 citations,
May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
25 citations,
May 2020 in “Aesthetic Surgery Journal” The regenerative solution, tSVF, is a safe and effective treatment for various conditions like aged skin, scars, wounds, and more, but more research is needed to find the best way to use it.
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November 2019 in “Cell calcium” The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
72 citations,
November 2017 in “Journal of developmental biology” The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.
47 citations,
August 2016 in “American Journal Of Pathology” Fibroblast changes in systemic sclerosis may help understand disease severity and treatment.
149 citations,
June 2010 in “The FASEB journal” miR-31 regulates hair growth by controlling gene expression in hair follicles.
88 citations,
August 2014 in “PLOS genetics” Syndecan-1 is essential for maintaining skin fat and preventing cold stress.