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Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Researchers found genetic mutations causing hypohidrotic ectodermal dysplasia in 88% of studied patients and identified new mutations and genetic variations affecting the disease.

Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Deleting Snai2 and Snai3 causes fatal autoimmunity.

The document reports findings on genetic research, including ethical concerns about genome editing, improved diagnosis of mitochondrial mutations, solving inherited eye diseases, confirming gene roles in epilepsy, linking a gene to aneurysms, and identifying genes associated with age-related macular degeneration.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

IL-33 is linked to hair follicle damage in psoriasis and could be a treatment target for hair loss in this condition.

Hair follicles can be used to quickly assess drug effects in cancer treatment.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.

Hard skin features like scales, feathers, and hair evolved through specific protein changes in different animal groups.

A protein in plants needs to bind two lipids to help with root hair growth, and this process is similar across different plant species.

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.

Keratins are important for skin cell health and their problems can cause diseases.

Changes in keratin affect skin health and can lead to skin disorders like blistering diseases and psoriasis.

Keratin mutations cause skin diseases and could lead to new treatments.

Improved technique for facial surgery hides scars and maintains hairline.

Keratin-based particles safely improve hair strength, smoothness, and heat protection.

Hidradenitis Suppurativa has genetic links, with certain gene mutations more common in patients and a third of cases having a family history.

The document concludes that adenosine receptor agonists have potential for treating various conditions, but only a few are approved due to challenges like side effects and the need for selective activation.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Cyclosporin A helps mice grow hair by blocking a specific protein activity in skin cells.

Uncombable hair syndrome causes frizzy hair and can affect the nervous system, eyes, and ears, often co-occurring with other hair, skin, nail, and teeth conditions, and is linked to three specific gene mutations.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

The research found that postmortem root bands in hair are likely caused by the breakdown of a specific part of the hair's inner structure after death.

A new method accurately measures amino acids in treated hair, showing bleaching reduces amino acids while protein treatments increase them.