research Large-Scale Multicenter Prospective Registry Study of Ripretinib in Advanced GIST: A Real-World Study from China
Ripretinib is effective and safe for treating advanced GIST in Chinese patients, particularly for non-gastric GISTs.
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research Brazilian Pulmonology Guidelines on Delphi Panel for Post-Coronavirus Disease 2019
Experts agree on the need for standardized definitions and education for post-COVID-19 conditions.
research Can We Halt Male Androgenetic Alopecia Progression Without Antiandrogenic Drugs?
Only anti-androgenic drugs likely halt AGA progression.
research Prospective Evaluation of Blood Pressure, Heart Rate, and Side Effects in Hypertensive Patients Using Low-Dose Oral Minoxidil for Hair Loss
Low-dose oral minoxidil is generally safe for hypertensive patients with hair loss.
research Oral Minoxidil 7.5 mg for Hair Loss Increases Heart Rate with No Change in Blood Pressure in 24-Hour Holter and 24-Hour Ambulatory Blood Pressure Monitoring
Oral minoxidil 7.5 mg for hair loss increases heart rate but not blood pressure.
research Efficacy of 5% Topical Minoxidil Versus 5 Mg Oral Biotin Versus Topical Minoxidil and Oral Biotin on Hair Growth in Men: Randomized, Crossover, Clinical Trial
Using both minoxidil and biotin together increased hair growth more than using either one alone.
research Oral Minoxidil Versus Topical Minoxidil for Male Androgenetic Alopecia
Oral minoxidil is as effective as topical minoxidil for male hair loss but has more side effects like excessive hair growth and headaches.
research Repigmentation in Skin of Color After Phenol-Croton Oil Chemical Peel
Skin of color can spontaneously repigment after a phenol-croton oil chemical peel.
research Profiling UK Injectable Aesthetic Practitioners: A National Cohort Analysis
The study shows the UK's injectable aesthetic industry is diverse and under-regulated, posing risks to patients.
research Agaricus Subrufescens Ameliorates Ovarian Dysfunction in Rats with Letrozole Induced Polycystic Ovarian Syndrome
Agaricus subrufescens extract improved ovarian function and normalized various health markers in rats with PCOS.
research Female Pattern Hair Loss: Therapeutic Update
Topical minoxidil is the best-supported treatment for female hair loss, but personalized plans are needed.
research Indications, Efficacy, and Side Effects of Oral Minoxidil: An Integrative Review
research Development and Validation of a Dermoscopic Severity Score for Female Pattern Hair Loss
A reliable severity score for female pattern hair loss was developed and validated.
research JAAD – Prevalence of Female Pattern Hair Loss in a Multiracial Population
research Adverse Effects of Low-Dose Oral Minoxidil for Androgenetic Alopecia in 435 Patients
research DSP c.6310delA p.(Thr2104Glnfs*12) Associates With Arrhythmogenic Cardiomyopathy, Increased Trabeculation, Curly Hair, and Palmoplantar Keratoderma
A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.
research Evaluation of Defensive Responses Associated with Panic in Female Rats: Serotonergic Activation Profile in the Dorsal Raphe Nucleus and Periaqueductal Gray
Female rats showed more panic-related behavior than males, influenced by hormonal cycles and certain drugs.
research Finasteride Reduces Microvessel Density and Expression of Vascular Endothelial Growth Factor in Renal Tissue of Diabetic Rats
Finasteride helps reduce blood vessel growth in diabetic rat kidneys.
research Overview of Lichen Planopilaris: Diagnosis and Treatment
Lichen Planopilaris is a hair loss condition best treated early with various medications, including hydroxychloroquine, to prevent permanent baldness.
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome
The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
research Revised 2003 Consensus on Diagnostic Criteria and Long-Term Health Risks Related to Polycystic Ovary Syndrome (PCOS)
The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
research The Androgen Excess and PCOS Society Criteria for the Polycystic Ovary Syndrome: The Complete Task Force Report
The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
research The Rotterdam Study: 2016 Objectives and Design Update
The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.
research The Current Landscape for Direct-to-Consumer Genetic Testing: Legal, Ethical, and Policy Issues
The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.
research Epigenetic Control of Adult Stem Cell Function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
research Lupus Erythematosus: Systemic and Cutaneous Manifestations
Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.
research Selenium as an Element in the Treatment of Ovarian Cancer in Women Receiving Chemotherapy
Taking selenium supplements during chemotherapy may help reduce side effects and improve health markers in ovarian cancer patients.
research The Transcriptional Co-Activator cAMP Response Element-Binding Protein-Binding Protein Is Expressed in Prostate Cancer and Enhances Androgen- and Anti-Androgen-Induced Androgen Receptor Function
A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Folliculitis Keloidalis Nuchae and Pseudofolliculitis Barbae
These skin conditions in African men need combined medical treatments and lifestyle changes.