34 citations
,
January 2012 in “Journal of Dermatological Science” In this mouse study, researchers found that hydrogen peroxide and monoethanolamine in hair dyes may be key contributors to dermatitis and hair loss due to oxidative stress.
34 citations
,
July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
34 citations
,
January 2011 in “Annals of dermatology/Annals of Dermatology” This study found that using a hair dryer at 15 cm with continuous motion causes less surface damage to hair compared to natural drying, although higher temperatures increased overall surface damage.
34 citations
,
March 2009 in “British journal of dermatology/British journal of dermatology, Supplement” In this study, l-Ascorbic acid 2-phosphate was found to stimulate hair follicle growth in vitro by promoting IGF-1 expression via the PI3K pathway.
34 citations
,
March 2015 in “Clinical and Experimental Dermatology” This study observed that patients with pemphigus have a higher incidence of hypothyroidism, inflammatory bowel disease, and diabetes compared to the general population.
32 citations
,
December 2013 in “Biological & Pharmaceutical Bulletin” In this study, rice bran supercritical CO2 extract demonstrated potential to promote hair growth in mice, increasing hair follicles and growth factor expression, similarly to 3% minoxidil.
31 citations
,
October 2010 in “BMB Reports” In this study, L-threonate was found to inhibit DHT-induced DKK-1 expression in cultured dermal papilla cells, suggesting it could help prevent androgen-driven balding.
29 citations
,
June 2018 in “Scientific Reports” In this study, Alox15 knockout mice exhibited disrupted skin integrity and increased inflammation, suggesting that Alox15-mediated resolvin D2 production is crucial for maintaining skin homeostasis by suppressing inflammation.
29 citations
,
March 2010 in “Journal of Dermatological Science” This study found that Wnt3a increased beta-catenin signaling and upregulated specific genes in cultured human dermal papilla cells, enhancing their response to PGE2 and potentially aiding hair growth.
27 citations
,
May 2019 in “Jo'jig gonghag gwa jaesaeng uihag/Tissue engineering and regenerative medicine” This review discusses strategies and translational advancements in urethral tissue engineering, concluding that a combination of hypoxia-preconditioned mesenchymal stem cells on pre-vascularized synthetic scaffolds may be most effective; it reports no new clinical results.
26 citations
,
January 2014 in “Annals of Dermatology” This report describes a 33-year-old woman who developed alopecia neoplastica due to gastric adenocarcinoma, highlighting the role of tumor invasion in hair follicle atrophy.
25 citations
,
November 2001 in “Kidney International” This study suggests that dihydrotestosterone plays a key role in the development of chronic allograft nephropathy, and inhibiting androgens may improve long-term kidney transplant outcomes.
23 citations
,
June 2015 in “Oncology Letters” This study reported that adipose-derived stem cell-conditioned medium demonstrated anti-tumorigenic effects on B16 melanoma cells both in vitro and in vivo, indicating potential for future melanoma treatment.
22 citations
,
October 2018 in “Molecular Medicine Reports” In this study, classic PDRN (50-1,500 kDa) was observed to improve wound healing quality in a mouse model by enhancing collagen composition and cell migration.
21 citations
,
January 2013 in “Clinical Endoscopy” This study reports the first case in South Korea of Cronkhite-Canada syndrome associated with malignant colon polyp and serrated adenoma.
20 citations
,
December 2013 in “Clinical and Experimental Dermatology” This study found that among Korean men with AGA, drinking and smoking were associated with greater hair loss severity, while family history was linked to more severe hair loss and earlier onset.
20 citations
,
July 2006 in “Annals of Anatomy - Anatomischer Anzeiger” The 15th-century Korean mummy's hair was well-preserved due to a protective lime-soil coating.
19 citations
,
January 2012 in “Dermatology” This study describes three cases of acneiform eruptions from EGFR inhibitors that improved with topical recombinant human EGF, suggesting its potential as a treatment option for this side effect.
18 citations
,
September 2023 in “Experimental Dermatology” This review examines the role of skin microbes in enhancing the skin barrier and their involvement in skin diseases like atopic dermatitis, while also discussing current and future therapeutic strategies targeting the skin microbiome.
18 citations
,
April 2010 in “Journal of Chromatography B” This study describes a validated UPLC-MS/MS method for quantifying finasteride in human plasma, demonstrating higher specificity, improved resolution, increased sensitivity, and faster analysis times compared to conventional HPLC-MS/MS methods.
17 citations
,
September 2024 in “Journal of Ginseng Research” This review discusses recent in vitro and in vivo research suggesting that components of ginseng, such as ginsenosides and gintonin, may have potential skincare benefits, including anti-aging effects and treatment of skin conditions like atopic dermatitis and hypertrophic scars.
17 citations
,
January 2022 in “Annals of Dermatology” In this study, the severity of pediatric alopecia areata was found to decrease the quality of life for both patients and their families while increasing the overall burden.
17 citations
,
February 2016 in “Experimental Dermatology” This study found that SFRP2 enhances Wnt3a-mediated β-catenin signaling in human dermal papilla cells, with higher SFRP2 expression in beard cells correlating with increased trichogenicity.
17 citations
,
May 2010 in “Journal of Dermatological Science” This study found that erythropoietin promotes hair growth by stimulating dermal papilla cells with functional erythropoietin receptors, enhancing hair shaft elongation and anagen phase in cultured human hair follicles and in mice.
16 citations
,
January 2018 in “Biochemical and Biophysical Research Communications” In this study, researchers established five new immortalized human dermal papilla cell lines from a male with androgenetic alopecia, which may serve as valuable tools for hair research.
16 citations
,
October 2012 in “The Journal of Dermatology” This study found that the BASP classification system for pattern hair loss showed better reproducibility and repeatability compared to the Norwood-Hamilton classification.
15 citations
,
April 2022 in “Ginekologia Polska” Higher thyroid hormone levels may be linked to certain types of polycystic ovary syndrome.
15 citations
,
January 2016 in “Biological & Pharmaceutical Bulletin” This study found that bee venom promoted hair growth in mice and inhibited a key enzyme involved in testosterone conversion, suggesting its potential as a 5α-reductase inhibitor and hair growth promoter.
14 citations
,
May 2021 in “Marine Drugs” This review discusses the therapeutic properties of polydeoxyribonucleotides derived from marine organisms for wound healing and inflammation, but it reports no new clinical results.
14 citations
,
April 2021 in “International journal of molecular sciences” This study found that human hematopoietic mesenchymal stem cells increased the viability and migration of human outer root sheath cells in an in vitro alopecia areata model, involving Wnt/β-catenin and JAK/STAT pathways.