June 2024 in “Research Square (Research Square)” In this study, researchers identified nine FDA-approved drugs that activate the Wnt signaling pathway, with Aminoacridine, especially when combined with Minoxidil, showing promising effects on hair and nail growth in mice, suggesting potential treatments for hair and nail loss pending further clinical trials.
June 2024 in “International journal of molecular sciences” In this study, researchers found that topical treatment with adenosine improved hair growth and thickness by significantly increasing hair density and thickness after four months in vivo, with results comparable to minoxidil, potentially due to adenosine's anti-androgenic effects.
May 2024 in “Journal of cosmetic dermatology” This study investigated the effects of heat-treated Limosilactobacillus fermentum LM1020 on hair growth and reported increased hair density, improved cellular activity, and beneficial scalp microbiota changes in patients with androgenetic alopecia over 24 weeks.
April 2024 in “Journal of microbiology and biotechnology” The authors will correct the table to show the right antibody information.
April 2024 in “JCEM case reports” This case report highlights a persistent gynecomastia in a young man following low-dose finasteride, suggesting that the incidence may be underreported and calls for patient counseling and early intervention.
April 2024 in “Journal of wildlife diseases” This study reported that captive muskoxen in Fairbanks, Alaska have significantly faster and variable guard hair growth rates compared to free-ranging Greenland muskoxen, indicating that a universal hair growth rate cannot be applied across different muskox populations or time periods.
April 2024 in “Human genomics” This study identified MPB susceptibility genes and potential drug candidates that may help uncover molecular mechanisms and address male-pattern baldness.
March 2024 in “Nutrients” This study found that Gynostemma pentaphyllum leaf hydrodistillate (GPHD) promoted hair growth in mice similarly to minoxidil and upregulated growth factor expression via the AKT/β-catenin signaling pathway, with damulin B identified as an active component contributing to these effects.
March 2024 in “Journal of pharmacopuncture” In this study, a patient with stress-induced Alopecia areata treated eight times with Hominis Placenta Pharmacopunture showed new terminal hair growth and a reduced lesion size, suggesting potential effectiveness of this treatment for the condition.
February 2024 in “Research Square (Research Square)” This study identified SFRP2 and PTGDS as potential biomarkers for female pattern hair loss, finding these genes consistently upregulated in bald hair follicles from all 18 patients, which may contribute to understanding the condition's pathogenesis and developing targeted treatments.
February 2024 in “International journal of molecular sciences” This study established an animal model using UV-irradiated C57BL/6 mice to assess hair luster, reporting that UV exposure alters keratin-associated protein gene expression, and suggested potential for developing effective hair care products by evaluating treatments like oral minoxidil.
January 2024 in “Diabetes & metabolism journal” This review explored how the circadian system might influence diabetes development and management, highlighting mismatches like disrupted sleep-wake cycles and gene mutations that could worsen diabetes, and suggests targeting these for future diabetes prevention and treatment strategies.
January 2024 in “Research Square (Research Square)” This study identified robust susceptibility genes and potential drug candidates for male-pattern baldness, providing insights into the condition's molecular mechanisms.
January 2024 in “Journal of tissue engineering” In this study, researchers used a human skin organoid model to show that solar UV exposure damages hair follicles and skin, while exosomes from mesenchymal stem cells reduced inflammation and supported hair follicle regeneration.
December 2023 in “Expert Opinion on Drug Safety” This abstract raises concerns about the safety of finasteride, a medication often used for treating hair loss and prostate issues, due to emerging reports linking it to cognitive dysfunction.
December 2023 in “Scientific Reports” In this study, researchers successfully established immortalized human frontal and occipital scalp dermal papilla cell lines from androgenetic alopecia patients, observing distinct gene expression, androgen receptor levels, and hair follicle growth effects between these regions, which may help advance hair loss research and therapeutic development.
October 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” In this study, the researchers found that awareness of appearance due to hair loss positively impacted hair loss management behaviors through self-awareness and psychological factors, but appearance management intention did not influence care behaviors.
October 2023 in “Applied materials today” In this study, researchers developed a novel TA-encapsulated microneedle applicator that successfully promoted hair growth and reduced inflammation in a C3H/HeJ mouse model of alopecia areata, potentially offering an improved alternative to existing treatments.
October 2023 in “Scientific reports” In this study, researchers found that the synthetic stress hormone dexamethasone caused opposite effects on hair growth-related proteins, reducing SFRP2 and increasing SFRP3, which respectively stimulate and inhibit hair follicle cell proliferation in human dermal papilla cells.
September 2023 in “Journal of microbiology and biotechnology” This study found that low molecular weight collagen peptide from fish may promote hair growth in both human cells and mice by activating the Wnt/β-catenin signaling pathway.
September 2023 in “Journal of The American Academy of Dermatology” This study found that adolescents with androgenetic alopecia showed distinct hormonal profiles between boys and girls, with concurrent metabolic dysfunction present in both sexes, highlighting the need for sex-specific diagnosis and management approaches.
August 2023 in “Han'gug miyong haghoeji/Journal of the Korean society of cosmetology” In this study, text mining revealed that research on natural materials effective for hair—focusing on growth, damage, and dyeing—has increased since 2001, indicating rising academic interest and exploring trends in beauty-related topics.
August 2023 in “Skin Research and Technology” This study found that using planimetric surface area measurement might be a useful supplementary method to improve the accuracy of SALT scoring in alopecia areata, particularly for scores S1 to S3.
August 2023 in “Skin Research and Technology” In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.
This study suggests that Nepenthes kampotiana Lecomte ethanol extract may promote hair growth and inhibit cell death in models of androgenic alopecia, indicating potential as a treatment option.
In this study, Korean patients with systemic lupus erythematosus had a worse perception of the COVID-19 vaccine compared to the influenza vaccine, with higher reported adverse events and concerns about causing lupus flares.
June 2023 in “Hanguk ingeurie hakoeji” This study found that consuming a fermented protein mixture for 60 days may increase hair density in healthy adults, although it did not significantly change other scalp or hair conditions like thickness, pore condition, or blood vessel exposure.
In this study, Korean patients with systemic lupus erythematosus reported worse perceptions and higher adverse events with the COVID-19 vaccine compared to the influenza vaccine.
This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.
March 2023 in “Scientific reports” This study presents evidence that hair matrix progenitors and the enzyme Stearoyl CoA Desaturase 1 may play a role in maintaining the dermal papilla niche via autocrine Wnt and paracrine Hedgehog signaling in mice.