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Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.

Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.

Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Skin problems can be caused or worsened by physical forces and pressure on the skin.

Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Wound healing insights can improve regenerative medicine.