87 citations,
April 2018 in “Biochemical and Biophysical Research Communications” Exosomes from dermal papilla cells can help grow hair and might treat hair loss.
1 citations,
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical patidegib gel effectively treats basal cell carcinoma in Gorlin syndrome patients without causing the side effects seen with oral treatments.
23 citations,
May 2020 in “Cell Death and Disease” Blocking the FGF5 gene in sheep leads to more fine wool and active hair follicles due to changes in certain cell signaling pathways.
2 citations,
November 2023 in “Biomolecules” WNT signaling is crucial for skin development and healing.
3 citations,
September 2022 in “Frontiers in veterinary science” Melatonin affects cashmere growth in goats by influencing stem cell and certain signaling pathways.
June 2010 in “Melanoma research” LDE225 is a promising skin-applied treatment for basal cell carcinoma with good skin penetration and effectiveness.
1 citations,
January 2011 in “International Journal of Trichology” Hair follicle stem cells have significant potential for treating various disorders.
21 citations,
March 2019 in “Critical Reviews in Clinical Laboratory Sciences” The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.
21 citations,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.
1 citations,
October 2022 in “JCI insight” Deleting the BRD4 protein in certain skin cells causes hair loss and skin inflammation.
Activin A promotes ear hair cell development, while follistatin delays it.
128 citations,
August 2020 in “Cell stem cell” Dermal fibroblasts have adjustable roles in wound healing, with specific cells promoting regeneration or scar formation.
238 citations,
April 2012 in “Cell stem cell” Targeting and modifying the stem cell niche can improve regenerative therapies.
Activin A and follistatin control when ear hair cells form in mice.
25 citations,
December 2021 in “Stem Cell Research & Therapy” MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
5 citations,
February 2022 in “Frontiers in physiology” Hair graying is influenced by factors like nerves, fat cells, and immune cells, not just hair follicles.
3 citations,
May 2021 in “Archiv der Pharmazie” SUN11602 and ONO-1301 could help in skin healing and creating artificial skin.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
8 citations,
January 2014 in “Annals of Dermatology” The research suggests that p63 and TGF-β1 may help determine tumor type and malignancy in hair follicle and sebaceous tumors.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
5 citations,
September 2015 in “PubMed” Epigenetic changes are crucial for stem cell behavior in skin wound healing and their disruption may lead to cancer.
2 citations,
January 2023 in “International journal of biological sciences” Gray hair can potentially be reversed, leading to new treatments.
1 citations,
September 2015 in “Elsevier eBooks” SOX2 is crucial for skin cell function and hair growth, and it plays a role in skin cancer and wound healing.
November 2023 in “Frontiers in veterinary science” The study provides insights into hair growth mechanisms in yaks.
March 2023 in “International Journal of Biomedicine” Hair loss from Telogen Effluvium can be managed by treating the underlying cause and may improve with treatments like minoxidil.
November 2021 in “Austin therapeutics” Current treatments for hair loss from chemotherapy are limited, but new methods are being researched.
2 citations,
January 2023 in “Scientific Reports” HIF-1α is important for hair growth and could be a treatment target for hair loss.
37 citations,
November 2017 in “Medical Sciences” Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.
1 citations,
March 2022 in “IntechOpen eBooks” Aging reduces skin stem cell function, leading to changes like hair loss and slower wound healing.
Different genes and pathways are active in yak skin and hair cells, affecting hair growth and immune responses.