Search
for

    Sort by

    Research 30 of 1000+

    1. Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes Molecular and Cellular Biology · 2006 · 226 citations
    2. Conditional Disruption of Hedgehog Signaling Pathway Defines its Critical Role in Hair Development and Regeneration Journal of Investigative Dermatology · 2000 · 194 citations
    3. Hedgehog signalling in skin development and cancer Experimental Dermatology · 2006 · 190 citations
    4. Hedgehog stimulates hair follicle neogenesis by creating inductive dermis during murine skin wound healing Nature Communications · 2018 · 145 citations
    5. Phase I Study of the Hedgehog Pathway Inhibitor IPI-926 in Adult Patients with Solid Tumors Clinical Cancer Research · 2013 · 136 citations
    6. Characterization and Management of Hedgehog Pathway Inhibitor-Related Adverse Events in Patients With Advanced Basal Cell Carcinoma ˜The œoncologist · 2016 · 127 citations
    7. MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling Developmental Cell · 2010 · 118 citations
    8. Modulation of Hair Growth with Small Molecule Agonists of the Hedgehog Signaling Pathway Journal of Investigative Dermatology · 2005 · 113 citations
    9. Hedgehog signaling is essential for normal wound healing Wound Repair and Regeneration · 2008 · 112 citations
    10. Overexpression of Hedgehog Signaling Is Associated with Epidermal Tumor Formation in Vitamin D Receptor–Null Mice Journal of Investigative Dermatology · 2011 · 100 citations
    11. An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis Development · 2004 · 99 citations
    12. Roles of the Hedgehog Signaling Pathway in Epidermal and Hair Follicle Development, Homeostasis, and Cancer Journal of developmental biology · 2017 · 72 citations
    13. Hedgehog signaling maintains hair follicle stem cell phenotype in young and aged human skin Aging Cell · 2009 · 62 citations
    14. AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma Nature Communications · 2020 · 60 citations
    15. The Vitamin D Receptor Is Required for Activation of cWnt and Hedgehog Signaling in Keratinocytes Molecular Endocrinology · 2014 · 56 citations
    16. Disruption of the hedgehog signaling pathway contributes to the hair follicle cycling deficiency in Vdr knockout mice Journal of Cellular Physiology · 2010 · 53 citations
    17. WISP-1 induced by mechanical stress contributes to fibrosis and hypertrophy of the ligamentum flavum through Hedgehog-Gli1 signaling Experimental & Molecular Medicine · 2021 · 36 citations
    18. Hedgehog Signaling, Keratin 6 Induction, and Sebaceous Gland Morphogenesis American Journal Of Pathology · 2008 · 33 citations
    19. Hedonic sensitivity to natural rewards is affected by prenatal stress in a sex-dependent manner Addiction Biology · 2015 · 28 citations
    20. Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state Developmental cell · 2022 · 25 citations
    21. A Review of Hedgehog Inhibitors Sonidegib and Vismodegib for Treatment of Advanced Basal Cell Carcinoma Journal of drugs in dermatology · 2021 · 25 citations
    22. Hedgehog and Gli Signaling in Embryonic Mammary Gland Development Journal of mammary gland biology and neoplasia · 2013 · 25 citations
    23. Sonic Hedgehog signalling in the regulation of barrier tissue homeostasis and inflammation FEBS Journal · 2021 · 23 citations
    24. Hedgehog Pathway Inhibitors against Tumor Microenvironment Cells · 2021 · 21 citations
    25. Hes1 regulates anagen initiation and hair follicle regeneration through modulation of hedgehog signaling Stem Cells · 2019 · 20 citations
    26. From basal cell carcinoma morphogenesis to the alopecia induced by hedgehog inhibitors: connecting the dots British Journal of Dermatology · 2017 · 17 citations
    27. Basal Cell Carcinoma, Hedgehog Signaling, and Targeted Therapeutics: The Long and Winding Road Journal of Investigative Dermatology · 2014 · 15 citations
    28. Exosomes Derived From Human Adipose-Derived Stem Cells Inhibit Lipogenesis Involving Hedgehog Signaling Pathway Frontiers in Bioengineering and Biotechnology · 2021 · 13 citations
    29. LncRNA-XIST promotes dermal papilla induced hair follicle regeneration by targeting miR-424 to activate hedgehog signaling Cellular Signalling · 2020 · 11 citations
    30. Evaluation of the Tolerability of Hedgehog Pathway Inhibitors in the Treatment of Advanced Basal Cell Carcinoma: A Narrative Review of Treatment Strategies American Journal of Clinical Dermatology · 2024 · 10 citations